Anti-PMS2 (D483) Antibody

PMS2 antibody

Boster Bio Anti-PMS2 (D483) Antibody catalog # A01028-2. Tested in IHC,IF applications. This antibody reacts with Human,Mouse,Rat.

Product Info Summary

SKU: A01028-2
Size: 100ul
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: IF, IHC

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Product Name

Anti-PMS2 (D483) Antibody

View all PMS2 Antibodies

SKU/Catalog Number

A01028-2

Size

100ul

Form

Liquid

Description

Boster Bio Anti-PMS2 (D483) Antibody catalog # A01028-2. Tested in IHC,IF applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-PMS2 (D483) Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01028-2)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human IRAK-1 around the phosphorylation site of T209.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A01028-2 is reactive to PMS2 in Human, Mouse, Rat

Applications

A01028-2 is guaranteed for IF, IHC Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

95.797kDa

Background of PMS2

4E-BP1 encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Gingras AC, et al. (1998) Genes Dev 12(4): 502-513.
Brugarolas J, et al. (2004) Genes Dev 18(23): 2893-2904.
Kumar V, et al. (2000) EMBO J 19(5): 1087-1097.
Moody CA, et al. (2005) J Virol 79(9): 5499-5506.
Burnett PE, et al. (1998) Proc Natl Acad Sci U S A 95(4): 1432-1437.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

IHC: 1:50-1:200
IF: 1:50-1:200

Validation Images & Assay Conditions

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Gene/Protein Information For PMS2 (Source: Uniprot.org, NCBI)

Gene Name

PMS2

Full Name

Mismatch repair endonuclease PMS2

Weight

95.797kDa

Superfamily

DNA mismatch repair MutL/HexB family

Alternative Names

DNA mismatch repair protein PMS2; EC 3.1; H_DJ0042M02.9; HNPCC4postmeiotic segregation increased (S. cerevisiae) 2; mismatch repair endonuclease PMS2; PMS1 protein homolog 2; PMS2 postmeiotic segregation increased 2 (S. cerevisiae); PMSL2PMS2CL PMS2 HNPCC4, MLH4, MMRCS4CL, PMSL2, PMS2 PMS1 homolog 2, mismatch repair system component mismatch repair endonuclease PMS2|DNA mismatch repair protein PMS2|PMS1 homolog 2, mismatch repair protein|PMS1 protein homolog 2|PMS2 postmeiotic segregation increased 2|postmeiotic segregation increased 2 nirs variant 6

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on PMS2, check out the PMS2 Infographic

PMS2 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for PMS2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A01028-2-100ul

100ul

$405

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A01028-2
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*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
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