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- Table of Contents
PTGES3 Antibodies
AND PTGES3 ELISA kits, PTGES3 Proteins
Many biological assays use antibodies to detect PTGES3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PTGES3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PTGES3 antibodies...
Designing a Western blot for PTGES3? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the PTGES3 Western Blot GuidePTGES3 Infographic by Boster Bio
All PTGES3 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, ICC, WB
$370
Cat # M04136-3
100 μg/vial
Cat # M04136-3
100 μg/vial
Human, Mouse
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A04146-1
100 μg/vial
Cat # A04146-1
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A04148-2
100 μg/vial
Cat # A04148-2
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A04136-1
100 μg/vial
Cat # A04136-1
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A04138-1
100 µg/vial
Cat # A04138-1
100 µg/vial
Human, Mouse, Rat
ELISA, IF, IHC, WB
$380
Cat # A04136S113
100ul
Cat # A04136S113
100ul
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A04148-1
100 μg/vial
Cat # A04148-1
100 μg/vial
Human
$628
Cat # LS100885850
20 µg, 100 µg
Cat # LS100885850
20 µg, 100 µg
Human, Mouse, Rat
ELISA
$540
Cat # EKC2127
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2127
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1560
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1560
1 kit, containing one 96-well plate and all necessary reagents
PTGES3 Overview
Facts about Prostaglandin E synthase 3.
Prostaglandin E synthase 3 (PTGES3)
Cytosolic prostaglandin synthase which catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) (PubMed:10922363). Molecular chaperone which localizes to genomic response elements within an hormone-dependent fashion and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes (PubMed:11274138, PubMed:12077419).
Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 into the HSP90 pathway (PubMed:24711448). .
Gene Information
| Human | |
|---|---|
| Gene Name: | PTGES3 |
| Uniprot: | Q15185 |
| Entrez: | 10728 |
Family
| Belongs to: |
|---|
| p23/wos2 family |
Alternative Names
CPGES; cPGESp23; Cytosolic prostaglandin E2 synthase; Hsp90 co-chaperone; p23; P23cytosolic prostaglandin E synthase; Progesterone receptor complex p23; prostaglandin E synthase 3 (cytosolic); prostaglandin E synthase 3; PTGES3; TEBP; TEBPEC 5.3.99.3; Telomerase-binding protein p23; unactive progesterone receptor, 23 kD
Molecular Weight
Mass (kDA):
18.697 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12q13.3|12 |
| Sequence: | 12; NC_000012.12 (56663341..56689575, complement) |
Subcellular Localizations
Cytoplasm.
Diseases
- Pseudopregnancy
- Hypertrophy
- Asthma
- Endometrial Polyp
- Dysequilibrium Syndrome
- Left Ventricular Hypertrophy
Interacting Proteins
- AGO2
- HSP90AA1
- HSP90AB1
- IRS4
Pathways
- Decidualization
- Parturition
- Fertilization
- Pathogenesis
- Meiosis
PTMs
Research Areas
- Membrane Trafficking and Chaperones
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PTGES3
bosterbio.com/bosterbio-gene-info-cards/PTGES3
References
PMID: 8114727 by Johnson J.L., et al. Characterization of a novel 23-kilodalton protein of unactive progesterone receptor complexes.
PMID: 11274138 by Forsythe H.L., et al. Stable association of hsp90 and p23, but Not hsp70, with active human telomerase.