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- Table of Contents
ACADVL Antibodies
AND ACADVL ELISA kits, ACADVL Proteins
Many biological assays use antibodies to detect ACADVL, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ACADVL in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ACADVL antibodies...
Designing a Western blot for ACADVL? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the ACADVL Western Blot GuideDesigning an IHC experiment for ACADVL? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the ACADVL IHC GuideACADVL Infographic by Boster Bio
All ACADVL Products
Product
Figures
Specificity
Applications
Price
Anti-ACADVL Antibody Picoband®
1 Citations
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # PB10023
100 μg/vial
Cat # PB10023
100 μg/vial
ACADVL Overview
Facts about Very long-chain specific acyl-CoA dehydrogenase, mitochondrial.
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADVL)
Active toward esters of long-chain and very long chain fatty acids such as palmitoyl-CoA, myristoyl-CoA and stearoyl-CoA. Can accommodate substrate acyl chain lengths as long as 24 carbons, but shows little action for substrates of less than 12 carbons.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | ACADVL |
| Uniprot: | P49748 |
| Entrez: | 37 |
Family
| Belongs to: |
|---|
| acyl-CoA dehydrogenase family |
Alternative Names
ACAD6; acyl-CoA dehydrogenase, very long chain; acyl-Coenzyme A dehydrogenase, very long chain; EC 1.3.99; EC 1.3.99.-; LCACD; very long-chain specific acyl-CoA dehydrogenase, mitochondrial; VLCAD
Molecular Weight
Mass (kDA):
70.39 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17p13.1 |
| Sequence: | 17; NC_000017.11 (7217125..7225267) |
Subcellular Localizations
Mitochondrion inner membrane.
Diseases
- Long Chain Acyl-coa Dehydrogenase Deficiency
- Acyl-coa Dehydrogenase, Very Long-chain Deficiency
- Malignant Neoplasms
- Neoplasms
- Hypoglycemia
- Cardiomyopathies
- Multiple Acyl Coenzyme A Dehydrogenase Deficiency
- Mitochondrial Diseases
- Carcinoma
- Myopathy
- Diabetes Mellitus
Pathways
- Fatty Acid Oxidation
- Fatty Acid Beta-oxidation
- Pathogenesis
- Transport
- Lactation
- Parturition
- Oxidative Phosphorylation
- Reverse Transcription
- Cell Proliferation
- Aerobic Respiration
- Cell Development
- Proteolysis
PTMs
- Oxidation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ACADVL
bosterbio.com/bosterbio-gene-info-cards/ACADVL
References
PMID: 7668252 by Aoyama T., et al. Cloning of human very-long-chain acyl-coenzyme A dehydrogenase and molecular characterization of its deficiency in two patients.
PMID: 8845838 by Andresen B.S., et al. Cloning and characterization of human very-long-chain acyl-CoA dehydrogenase cDNA, chromosomal assignment of the gene and identification in four patients of nine different mutations within the VLCAD gene.