ACAT1 Antibodies

AND ACAT1 ELISA kits, ACAT1 Proteins

Many biological assays use antibodies to detect ACAT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ACAT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ACAT1 antibodies...

We validate the specificity of these antibodies to ACAT1 by testing them on tissues known to express ACAT1 positively and negatively. Browse below to find the ACAT1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ACAT1 Infographic by Boster Bio

All ACAT1 Products

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Specificity

Applications

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Anti-ACAT1 (K266) Antibody

Western blot (WB) analysis of ACAT-1 (K266) pAb at 1:1000 dilution
Lane1:HEK293T whole cell lysate(20ug)
Lane2:HepG2 whole cell lysate(20ug)
Lane3:The Lung tissue lysate of Rat(20ug)
Lane4:The Lung tissue lysate of Mouse(10ug)

Immunohistochemistry (IHC) analyzes of ACAT1 (K266) pA bin paraffin-embedded human liver carcinoma tissue at 1:50,showing cytoplasmic staining

Immunohistochemistry (IHC) analyzes of ACAT1 (K266) pA bin paraffin-embedded human kidney carcinoma tissue at 1:50,showing cytoplasmic staining

Human, Mouse, Rat

IHC, WB

$405
Cat # A02008
100ul

Human ACAT1 Recombinant Protein

SDS-PAGE

$250
Cat # PROTP24752
Starting from 20ug

Anti-ACAT1 Rabbit Monoclonal Antibody

Western blot analysis of ACAT1 using anti-ACAT1 antibody (M02008)

Immunoprecipitate (IP) analysis using the Antibody at 1:50 dilution

Human, Mouse, Rat

IP, IHC, WB

$370
Cat # M02008
100 μl/vial

Anti-ACAT1 Antibody Picoband®

Western blot analysis of ACAT1 using anti-ACAT1 antibody (A02008-1)

IHC analysis of ACAT1 using anti-ACAT1 antibody (A02008-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A02008-1
100 µg/vial

ACAT1 Overview

Facts about Acetyl-CoA acetyltransferase, mitochondrial.

ACAT1 3D structure. Source: alphafold

Acetyl-CoA acetyltransferase, mitochondrial (ACAT1)

Plays a significant role in ketone body metabolism. .

Gene Information

Human
Gene Name:	ACAT1
Uniprot:	P24752
Entrez:	38

Family

Belongs to:

thiolase-like superfamily

Alternative Names

ACAT; ACAT1; acetoacetyl Coenzyme A thiolase; Acetoacetyl-CoA thiolase; acetyl-CoA acetyltransferase 1; acetyl-CoA acetyltransferase, mitochondrial; acetyl-Coenzyme A acetyltransferase 1; EC 2.3.1; EC 2.3.1.9; MAT; mitochondrial acetoacetyl-CoA thiolase; T2; THIL

Molecular Weight

Mass (kDA):
45.2 kDA

Genomic Context


Human

Location:	11q22.3
Sequence:	11; NC_000011.10 (108116705..108148822)

Subcellular Localizations

Mitochondrion.

Diseases

Atherosclerosis
Hypercholesterolemia
Cardiovascular Diseases
Arteriosclerosis
Alzheimer's Disease
Hyperlipidemia
Malignant Neoplasms
Neoplasms
Hypertensive Disease
Liver Carcinoma
Dental Plaque
Atheroma

Obesity
Malignant Neoplasm Of Breast
Coronary Artery Disease
Neurodegenerative Disorders
Hypokinesia
Tissue Adhesions
Coronary Heart Disease

Pathways

Cholesterol Homeostasis
Secretion
Cholesterol Esterification
Cholesterol Efflux
Intestinal Cholesterol Absorption
Localization
Translation
Lipid Homeostasis
Excretion
Cell Adhesion
Transport
Cell Death
Pathogenesis

Sterol Esterification
Inflammatory Response
Cell Cycle
Lipid Binding
Response To Cholesterol
Cell Proliferation
Cholesterol Storage

PTMs

Acetylation
Phosphorylation
Cleavage

Reduction
Glycosylation
Oxidation

Acylation

Research Areas

Cancer
Cellular Markers
Lipid and Metabolism
Mitochondrial Markers
Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ACAT1

References

PMID: 1979337 by Fukao T., et al. Molecular cloning and sequence of the complementary DNA encoding human mitochondrial acetoacetyl-coenzyme A thiolase and study of the variant enzymes in cultured fibroblasts from patients with 3- ketothiolase deficiency.

PMID: 1684944 by Kano M., et al. Structure and expression of the human mitochondrial acetoacetyl-CoA thiolase-encoding gene.