ACP2 Antibodies

Lysosomal acid phosphatase (ACP2)

Gene Information

Human
Gene Name:	ACP2
Uniprot:	P11117
Entrez:	53

Family

Belongs to:
histidine acid phosphatase family

Alternative Names

acid phosphatase 2, lysosomal; EC 3.1.3.2; LAP; lysosomal acid phosphatase

Molecular Weight

Mass (kDA):
48.344 kDA

Genomic Context

Human
Location:	11p11.2|11p12-p11
Sequence:	11; NC_000011.10 (47239302..47248847, complement)

Subcellular Localizations

Lysosome membrane; Single-pass membrane protein; Lumenal side. Lysosome lumen. The soluble form arises by proteolytic processing of the membrane-bound form.

Diseases

• Malignant Neoplasms
• Amebiasis
• Legionnaires' Disease
• Hereditary Diseases
• Hyperplastic Polyp
• Cytopathic Effect
• Pittsburgh Pneumonia
• Neurodegenerative Disorders
• Acute Erythroblastic Leukemia
• Cell Invasion
• Liver Abscess
• Abscess
• Ataxia

• Swine Diseases
• Hepatitis B
• Progressive Supranuclear Palsy
• Carcinoma
• Neurocutaneous Syndromes
• Dysplasia
• Supranuclear Palsy

Pathways

• Localization
• Virulence
• Aging
• Cytokinesis
• Cell Growth
• Pathogenesis
• Rna Interference
• Transport
• Mitosis
• Proteolysis
• Disease Resistance
• Phagocytosis

• Cell Cycle
• Cell Differentiation
• Primary Growth
• Interphase
• Secretion
• Oncogenesis

PTMs

• Phosphorylation

• Cleavage

• Dephosphorylation

Research Areas

• Protein Phosphatase

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ACP2

Anti-ACE2 (K465) Antibody From Boster Bio

You've probably been looking for anti-ACE2 (K465) antibodies and their uses in research. You don't have to worry about it, as this article will provide all the information that you need to make a well-informed decision. Listed below are some of Boster's best products. They are high-affinity primary antibodies that have been validated and cited by the research community.

Anti-ACE2 (K465) Antibody

Boster Bio offers the Anti-ACE2 Antibody K465, which is used for blocking ACE2. This antibody can react with ACE2 protein in different animal samples. Boster Bio used mouse and rabbit models in the development of this antibody. ACE2 (angiotensin converting gene) is a member of the peptidase 2 family.

The ACE2 gene is a homolog of the ACE1 protein. ACE2 is a homolog to the ACE1 gene. It degrades angiotensin 2 to Ang(1-7), and plays other roles. Recent research has shown that activating the ACE2 genes by a synthetic molecule can have therapeutic effects. Autoantibodies against ACE2 were also associated with constrictive vascularopathies.

ACE2 is a protein that is found in the blood of many people with hypertension. It plays an important part in the body's defense from the SARS-CoV-2 viruses. ACE2 converts octapeptide Ang II to Ang(1-7), and inhibits AT1 receptor activity. This means that higher levels ACE2 can reduce blood pressure by blocking the AT1 receptor's effect.

Zinc and a binding inhibit are responsible for controlling the ACE2 enzyme. The enzyme was determined by ELISA using two sera from humans with significant autofluorescence. To determine the expression level of ACE2-Fc, a positive control antibody (antibody against ACE2-Fc) was used. The Anti-ACE2 Antibody from Boster Bio measured ACE2 enzyme activation. This antibody is useful for biochemical assays that measure ACE2-Fc in a cell.

The anti-SARS-CoV-2 activity of the plant-produced ACE2-Fc fusion protein was studied in vitro. It was expressed at 100 mg/g leaf fresh weight six days after infiltration. The fusion protein had potent anti-SARS/CoV-2 activity. Vero cells infected with ACE2-Fc fusion protein were inhibited by the fusion protein. The IC50 was 0.84 mg/ml.

Human ACE2 consists eight cysteine residues. Two of these are reversible. This prevents viral function and binding. SARS coronavirus is responsible for infections such as SARS. ACE2 is a receptor found on epithelial cells and is essential to prevent the disease spreading.

ACE2Marker

ACP2 is an ACP protein with many biological functions. It regulates the immune system and inhibits tumour activity. There are many species and types of ACPs. Their amino acid structure can be used to classify them. These proteins can be further subdivided into four categories: ACP2, ACP3, ACP4, and ACP5.

ACP modification can be effective in improving anti-tumour activity, but it does not overcome the cytotoxicity of the ACP. This is why further research on the biochemical and molecular biology of ACPs is essential. To guide the modification and application specific ACPs, further research is necessary. The ACP2 Marker: Best Uses

ACPs are short-chain peptides which are often modified via amino acid substitution. Amino acid substitution has several effects, including reducing net charge, increasing hydrophobicity, and improving selectivity. ACPs are better at fighting cancer cells because they are more electrically negative than normal cells. Hydrophobic interaction is particularly effective against tumour cells, and it has been shown to improve anti-tumour activity.

Antibody ACE2

The ACP2 protein, which is a universal marker of myocilin, is a component in cilia. It is found in both mouse and human cells. It is highly conserved in structure and sequence, and antibodies raised against this marker recognize it in both cell types. They have a high affinity and are cited frequently in scientific publications. This antibody recognizes myocilin in folded or denatured forms.

Its high affinity, selective binding affinity and high specificity make this a great candidate for screening antigens to detect amyloid and other misfolded proteins aggregates. It is useful for structural characterization and mechanistic studies of these aggregates as well as therapeutic applications. Because antibodies recognize different conformations, they can help determine which isoforms are involved in the occurrence and progression of disease. They can also lead to new drugs.

Steven Boster

This article will tell you all you need to know about Steven Boster and his ACP2 markers. Boster was an avid hunter. He had many ACP2 markers, and he used them to make many amazing portraits. The ACP2 marker is a high-quality camera, and the battery life is up to a year.