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- Table of Contents
Alpha-actinin-3 Antibodies
AND ACTN3 ELISA kits, Alpha-actinin-3 Proteins
Many biological assays use antibodies to detect Alpha-actinin-3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Alpha-actinin-3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Alpha-actinin-3 antibodies...
Designing a Western blot for Alpha-actinin-3? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the ACTN3 Western Blot GuideACTN3 Infographic by Boster Bio
All ACTN3 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, WB
$370
Cat # PB10026
100 μg/vial
Cat # PB10026
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, WB
$370
Cat # M02698-3
100 μg/vial
Cat # M02698-3
100 μg/vial
Human, Mouse, Rat
IHC, WB
$370
Cat # M02698-2
100 μg/vial
Cat # M02698-2
100 μg/vial
Human
Flow Cytometry, WB
$370
Cat # M02698-1
100 μg/vial
Cat # M02698-1
100 μg/vial
ACTN3 Overview
Facts about Alpha-actinin-3.
Alpha-actinin-3 (ACTN3)
F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | ACTN3 |
| Uniprot: | Q08043 |
| Entrez: | 89 |
Family
| Belongs to: |
|---|
| alpha-actinin family |
Alternative Names
actinin, alpha 3; Alpha-actinin skeletal muscle isoform 3; alpha-actinin skeletal muscle; alpha-actinin-3; F-actin cross-linking protein; MGC117002; MGC117005
Molecular Weight
Mass (kDA):
103.241 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11q13.2 |
| Sequence: | 11; NC_000011.10 (66546395..66563334) |
Tissue Specificity
Expressed only in a subset of type 2 skeletal muscle fibers.
Diseases
- Myopathy
- Pain
- Muscle Twitch
- Neuromuscular Diseases
- Glycogen Storage Disease Type V
- Muscle Weakness
- Fracture
- Muscular Dystrophy
- Cholangiocarcinoma
- Coronary Microvascular Disease
- Diabetes Mellitus
- Dystrophy
Interacting Proteins
- ACTN1
Pathways
- Cell Adhesion
- Aging
- Muscle Contraction
- Cell Proliferation
- Regulation Of Cell Adhesion
- Cell Development
- Response To Hypoxia
- Neurogenesis
- Metaphase
- Oxidative Phosphorylation
- Muscle Atrophy
- Spermatogenesis
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ACTN3
bosterbio.com/bosterbio-gene-info-cards/ACTN3
References
PMID: 1339456 by Beggs A.H., et al. Cloning and characterization of two human skeletal muscle alpha- actinin genes located on chromosomes 1 and 11.
PMID: 11440986 by Mills M., et al. Differential expression of the actin-binding proteins, alpha-actinin- 2 and -3, in different species: implications for the evolution of functional redundancy.
1 Publications of Boster Alpha-actinin-3 Antibodies & ELISA Kits
- PubMed ID: 10.1186/s13395-021-00279-0, Protein profile of fiber types in human skeletal muscle: a single-fiber proteomi...
*More publications can be found for each product on its corresponding product page