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- Table of Contents
Facts about Activin receptor type-1.
Receptor for activin. May be involved for left-right pattern formation during embryogenesis (By similarity).
Human | |
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Gene Name: | ACVR1 |
Uniprot: | Q04771 |
Entrez: | 90 |
Belongs to: |
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protein kinase superfamily |
activin A receptor, type I; Activin RIA; ActivinRIA; ACTRI; ACVR1; ACVR1A; ACVRLK2; ALK2; ALK-2; FOP; SKR1; TSRI
Mass (kDA):
57.153 kDA
Human | |
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Location: | 2q24.1 |
Sequence: | 2; NC_000002.12 (157736446..157876330, complement) |
Expressed in normal parenchymal cells, endothelial cells, fibroblasts and tumor-derived epithelial cells.
Membrane; Single-pass type I membrane protein.
PMID: 8389764 by Matsuzaki K., et al. A widely expressed transmembrane serine/threonine kinase that does not bind activin, inhibin, transforming growth factor beta, or bone morphogenic factor.
PMID: 8397373 by ten Dijke P., et al. Activin receptor-like kinases: a novel subclass of cell-surface receptors with predicted serine/threonine kinase activity.