- Table of Content
Probably involved in vesicular trafficking through its association with the CART complex. The CART complex is necessary for effective transferrin receptor recycling but not for EGFR degradation (PubMed:15772161).
|Sequence:||19; NC_000019.10 (38647649..38731589)|
Nucleus. Cytoplasm. Cell junction. Cytoplasm, cytoskeleton, stress fiber. Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Nuclear translocation can be induced by the PI3 kinase inhibitor wortmannin or by cytochalasin D. Exclusively localized in the nucleus in a limited number of cell lines (breast cancer cell line MCF-7, oral floor cancer IMC-2, and bladder cancer KU-7).
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