Product Info Summary
SKU: | M01975 |
---|---|
Size: | 100 μl |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | Flow Cytometry, IP, IF, IHC, ICC, WB |
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Product info
Product Name
Anti-alpha Actinin 4 ACTN4 Monoclonal Antibody
View all Alpha Actinin 4 Antibodies
SKU/Catalog Number
M01975
Size
100 μl
Form
Liquid
Description
Boster Bio Anti-alpha Actinin 4 ACTN4 Monoclonal Antibody catalog # M01975. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-alpha Actinin 4 ACTN4 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01975)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Clonality
Monoclonal
Clone Number
ACIO-1
Isotype
Rabbit IgG
Immunogen
A synthesized peptide derived from human alpha Actinin 4
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M01975 is reactive to ACTN4 in Human, Mouse, Rat
Applications
M01975 is guaranteed for Flow Cytometry, IP, IF, IHC, ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
104.854kDa
Background of Alpha Actinin 4
F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000
IHC 1:50-1:200
ICC/IF 1:50-1:200
IP 1:50
FC 1:50
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of alpha Actinin 4 expression in A431 cell lysate.
Protein Target Info & Infographic
Gene/Protein Information For ACTN4 (Source: Uniprot.org, NCBI)
Gene Name
ACTN4
Full Name
Alpha-actinin-4
Weight
104.854kDa
Superfamily
alpha-actinin family
Alternative Names
actinin alpha4 isoform; actinin, alpha 4; ACTININ-4; alpha-actinin-4; DKFZp686K23158; F-actin cross-linking protein; focal segmental glomerulosclerosis 1; FSGS; FSGS1; Non-muscle alpha-actinin 4 ACTN4 ACTININ-4, FSGS, FSGS1 actinin alpha 4 alpha-actinin-4|focal segmental glomerulosclerosis 1|non-muscle alpha-actinin 4
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ACTN4, check out the ACTN4 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ACTN4: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-alpha Actinin 4 ACTN4 Monoclonal Antibody (M01975)
Hello CJ!
M01975 has been cited in 2 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
Hu H,Xue J,Dong R,Zhao Y,Song C,Zhao H,Hescheler J,Zhang Y,Liang H.STAT3 Phosphorylation Mediating DMSO‘s Function on Fetal Cardiomyocyte Proliferation with Developmental Changes.Int Heart J.2019 Mar 20;60(2):392-399.doi:10.1536/ihj.18-206.Epub 2019 Feb 8.PMID:30745528.
Species: Mouse
M01975 usage in article: APP:IHC, SAMPLE:CARDIOMYOCYTES, DILUTION:1:100
STAT3 Phosphorylation Mediating DMSO's Function on Fetal Cardiomyocyte Proliferation with Developmental Changes Haitao Hu, et al. Int Heart J. 2019 Mar 20;60(2):392-399. doi: 10.1536/ihj.18-206. Epub 2019 Feb 8.
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