This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
AGR2 Antibodies
AND AGR2 ELISA kits, AGR2 Proteins
Many biological assays use antibodies to detect AGR2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AGR2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AGR2 antibodies...
Designing a Western blot for AGR2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the AGR2 Western Blot GuideDesigning an IHC experiment for AGR2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the AGR2 IHC GuideAGR2 Infographic by Boster Bio
All AGR2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # A02922-2
100 μg/vial
Cat # A02922-2
100 μg/vial
Human
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M02922
100 μl
Cat # M02922
100 μl
AGR2 Overview
Facts about Anterior gradient protein 2 homolog.
Anterior gradient protein 2 homolog (AGR2)
Required for MUC2 post-transcriptional secretion and synthesis. May play a role in the production of mucus by intestinal cells (By similarity).
Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth. Promotes cell adhesion (PubMed:23274113).
Gene Information
| Human | |
|---|---|
| Gene Name: | AGR2 |
| Uniprot: | O95994 |
| Entrez: | 10551 |
Family
| Belongs to: |
|---|
| AGR family |
Alternative Names
AG2; AG-2; AG2member 17; AGR2; anterior gradient 2 homolog (Xenopus laevis); anterior gradient homolog 2 (Xenopus laevis); GOB-4; hAG-2; HPC8; PDIA17; secreted cement gland homolog
Molecular Weight
Mass (kDA):
19.979 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7p21.1 |
| Sequence: | 7; NC_000007.14 (16791811..16804999, complement) |
Tissue Specificity
Expressed strongly in trachea, lung, stomach, colon, prostate and small intestine. Expressed weakly in pituitary gland, salivary gland, mammary gland, bladder, appendix, ovary, fetal lung, uterus, pancreas, kidney, fetal kidney, testis, placenta, thyroid gland and in estrogen receptor (ER)-positive breast cancer cell lines.
Subcellular Localizations
Secreted. Endoplasmic reticulum.
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Neoplasm Metastasis
- Malignant Neoplasm Of Breast
- Adenocarcinoma
- Mammary Neoplasms
- Prostatic Neoplasms
- Malignant Neoplasm Of Prostate
- Malignant Paraganglionic Neoplasm
- Cell Invasion
- Neoplasm Invasiveness
Interacting Proteins
- CATSPER1
- FABP2
- KRT31
- MUC2
- NUP62CL
- POM121
- SGTB
- UBQLN1
- UBQLN2
Pathways
- Cell Proliferation
- Pathogenesis
- Cell Migration
- Localization
- Regeneration
- Secretion
- Cell Differentiation
- Drug Resistance
- Cell Growth
- Cell Cycle
- Epithelial Cell Proliferation
- Protein Folding
- Rna Interference
PTMs
- Phosphorylation
Research Areas
- Breast Cancer
- Cancer
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AGR2
bosterbio.com/bosterbio-gene-info-cards/AGR2
References
PMID: 9790916 by Thompson D.A., et al. hAG-2, the human homologue of the Xenopus laevis cement gland gene XAG-2, is coexpressed with estrogen receptor in breast cancer cell lines.
PMID: 12592373 by Fletcher G.C., et al. hAG-2 and hAG-3, human homologues of genes involved in differentiation, are associated with oestrogen receptor-positive breast tumours and interact with metastasis gene C4.4a and dystroglycan.