AGTR2 Antibodies

AND AGTR2 ELISA kits, AGTR2 Proteins

Many biological assays use antibodies to detect AGTR2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AGTR2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AGTR2 antibodies...

We validate the specificity of these antibodies to AGTR2 by testing them on tissues known to express AGTR2 positively and negatively. Browse below to find the AGTR2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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AGTR2 Infographic by Boster Bio

All AGTR2 Products

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Applications

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Anti-AGTR2/Angiotensin Ii Type 2 Receptor Rabbit Monoclonal Antibody

4 Citations 6 Q&As

Western blot analysis of AGTR2 using anti-AGTR2 antibody (M00432)

Human, Mouse, Rat

IP, WB

$370
Cat # M00432
100 μl

Anti-Type-2 angiotensin II receptor AGTR2 Antibody

WB Validation in Mouse Tissues
Loading: 10 μg of lysate Antibodies: AGTR2, A00432-1, 2 μ g/mL , 1 h incubation at RT in 5% NFDM/TBST

WB Validation in Rat Heart
Loading: 15 μg of lysate Antibodies: AGTR2, A00432-1, 2 μg/mL , 1 h incubation at RT in 5% NFDM/TBST

Immunohistochemistry Validation of AGTR2 in Human Lung
Immunohistochemical analysis of paraffin-embedded human lung tissue using anti-AGTR2 antibody (A00432-1) at 1 μg/ml

Human, Mouse, Rat

ELISA, IF, IHC-P, ICC, WB

$481
Cat # A00432-1
0.1 mg

Angiotensin II Type 2 Receptor (AGTR2) (NM_000686) Human Over-expression Lysate

Human

$628
Cat # LS000186
20 µg, 100 µg

AGTR2 Overview

Facts about Type-2 angiotensin II receptor.

AGTR2 3D structure. Source: alphafold

Type-2 angiotensin II receptor (AGTR2)

Receptor for angiotensin II.
Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation.

Gene Information

Human
Gene Name:	AGTR2
Uniprot:	P50052
Entrez:	186

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

AGTR2; AGTR-2; Angiostensin Receptor; angiotensin II receptor, type 2; Angiotensin II type-2 receptor; angiotensin receptor 2; AT2; AT2ATGR2; AT2R; MRX88; MRX88type-2 angiotensin II receptor

Molecular Weight

Mass (kDA):
41.184 kDA

Genomic Context


Human

Location:	Xq23
Sequence:	X; NC_000023.11 (116170744..116174974)

Tissue Specificity

In adult, highly expressed in myometrium with lower levels in adrenal gland and fallopian tube. Expressed in the cerebellum. Very highly expressed in fetal kidney and intestine.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Hypertensive Disease
Congenital Abnormality
Kidney Diseases
Tumor Angiogenesis
Cholangiocarcinoma
Dysplasia
Renal Dysplasia
Inflammation
Neoplasms
Hypertrophy
Gastroesophageal Reflux Disease

Hydronephrosis
Ureteral Obstruction
Tissue Adhesions
Atherosclerosis
Vesico-ureteral Reflux
Brain Ischemia

Interacting Proteins

AGT
TIMP3

Pathways

Angiogenesis
Cell Proliferation
Secretion
Localization
Brain Development
Vasculogenesis
Tissue Remodeling
Pathogenesis
Excretion
Kidney Development
Transport
Muscle Cell Proliferation
Neurogenesis

Endothelial Cell Proliferation
Spermatogenesis
Inflammatory Response
Mrna Splicing
System Development
Cell Differentiation
Vasoconstriction

PTMs

Phosphorylation

Research Areas

Apoptosis

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AGTR2

References

PMID: 7733925 by Martin M.M., et al. The sequence and genomic organization of the human type 2 angiotensin II receptor.

PMID: 7790004 by Chassagne C., et al. Assignment of the human angiotensin II type 2 receptor gene (AGTR2) to chromosome Xq22-q23 by fluorescence in situ hybridization.

2 Publications of Boster AGTR2 Antibodies & ELISA Kits

PubMed ID: 10.1042/CS20200514, Antiepileptic effects of long-term intracerebroventricular infusion of angiotens...
PubMed ID: 10.1002/jcp.29862, Effect of angiotensin II and angiotensin‐(1–7) on proliferation of stem cell...

*More publications can be found for each product on its corresponding product page