AK1 Antibodies

AND AK1 ELISA kits, AK1 Proteins

Many biological assays use antibodies to detect AK1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AK1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AK1 antibodies...

We validate the specificity of these antibodies to AK1 by testing them on tissues known to express AK1 positively and negatively. Browse below to find the AK1 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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AK1 Infographic by Boster Bio

All AK1 Products

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Anti-Adenylate Kinase 1/AK1 Antibody Picoband®

4 Q&As

Western blot analysis of AK1 using anti-AK1 antibody (PB10033)

IHC analysis of AK1 using anti-AK1 antibody (PB10033)

Human, Mouse, Rat

Flow Cytometry, IHC, WB

$370
Cat # PB10033
100 μg/vial

Mouse Ak1 Recombinant Protein

3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain

Enzyme Activity, SDS-PAGE

$300
Cat # PROTQ9R0Y5
Starting from 10ug

Adenylate Kinase 1 (AK1) (NM_000476) Human Recombinant Protein

Coomassie blue staining of purified AK1 protein

$1062
Cat # PROTP00568
20 µg

Anti-Adenylate Kinase 1 (AK1) Mouse Monoclonal Antibody [Clone ID: OTI8A1]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY AK1 (Right lane) cDNA for 48 hrs and lysed

Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-AK1 monoclonal antibody

HEK293T cells transfected with either AK1 (Myc-DDK-tagged) overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-AK1 antibody (M01645)

Human, Monkey, Mouse, Rat

Flow Cytometry, IF, WB

$523
Cat # M01645
100 µl

Adenylate Kinase 1 (AK1) (NM_000476) Human Over-expression Lysate

Human

$628
Cat # LS000203
20 µg, 100 µg

AK1 Overview

Facts about Adenylate kinase isoenzyme 1.

AK1 3D structure. Source: alphafold

Adenylate kinase isoenzyme 1 (AK1)

Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity.

Plays an essential role in cellular energy homeostasis and in adenine nucleotide metabolism. .

Gene Information

Human
Gene Name:	AK1
Uniprot:	P00568
Entrez:	203

Family

Belongs to:

adenylate kinase family

Alternative Names

adenylate kinase 1; adenylate kinase isoenzyme 1; AK 1; ATP-AMP transphosphorylase 1; EC 2.7.4; EC 2.7.4.3; myokinase

Molecular Weight

Mass (kDA):
21.635 kDA

Genomic Context


Human

Location:	9q34.11
Sequence:	9; NC_000009.12 (127866480..127885542, complement)

Subcellular Localizations

Cytoplasm.

Diseases

Neoplasms
Tissue Adhesions
Nail-patella Syndrome
Anemia
Malignant Neoplasms
Anemia, Hemolytic
Tuberous Sclerosis
Sclerosis
Carcinoma
Dystonia Disorders
Dystonia Musculorum Deformans
Dysplasia
Diabetes Mellitus

Deficiency Of Adenylate Kinase
Classical Galactosemia
Hypoxia
Persistant Generalized Lymphadenopathy
Myocardial Ischemia
Cytogenetic Abnormality
Infective Disorder

Pathways

Localization
Glycolysis
Transport
Secretion
Cell Cycle
Rna Interference
Chromosome Localization
Energy Homeostasis
Regeneration
Oxidative Phosphorylation
Flight
Translation
Insulin Secretion

Cell Death
Cell Migration
Platelet Activation
Spermatogenesis
Nuclear Transport
Cell Division
Swimming

PTMs

Phosphorylation
Hydroxylation
Cleavage
Myristoylation

Nitrosylation
Carboxylation
Deamination
Oxidation

Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AK1

References

PMID: 183954 by von Zabern I., et al. Primary and tertiary structure of the principal human adenylate kinase.

PMID: 2542324 by Matsuura S., et al. Human adenylate kinase deficiency associated with hemolytic anemia. A single base substitution affecting solubility and catalytic activity of the cytosolic adenylate kinase.