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AKR1B10 Antibodies
AND AKR1B10 ELISA kits, AKR1B10 Proteins
Many biological assays use antibodies to detect AKR1B10, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AKR1B10 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AKR1B10 antibodies...
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AKR1B10 Infographic by Boster Bio
All AKR1B10 Products
Product
Figures
Specificity
Applications
Price
Anti-AKR1B10 Antibody Picoband®
1 Citations 7 Q&As
Human
IF, IHC, ICC, WB
$370
Cat # A02976
100 μg/vial
Cat # A02976
100 μg/vial
AKR1B10 Overview
Facts about Aldo-keto reductase family 1 member B10.
Aldo-keto reductase family 1 member B10 (AKR1B10)
Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro).
May be responsible for detoxification of reactive aldehydes from the digested food until the nutrients are passed on to other organs. .
Gene Information
| Human | |
|---|---|
| Gene Name: | AKR1B10 |
| Uniprot: | O60218 |
| Entrez: | 57016 |
Family
| Belongs to: |
|---|
| aldo/keto reductase family |
Alternative Names
AKR1B10; AKR1B11; AKR1B12; Aldo-keto Reductase 1B10; aldo-keto reductase family 1 member B10; aldo-keto reductase family 1, member B10 (aldose reductase); aldo-keto reductase family 1, member B11 (aldose reductase-like); AldoketoReductase 1B10; aldose reductase-like 1; aldose reductase-like peptide; Aldose reductase-like; Aldose reductase-related protein; ALDRLn; ARL1; ARL-1SI reductase; ARP; EC 1.1.1; EC 1.1.1.-; EC 1.1.1.21; hARP; HIS; HSI; MGC14103; Small intestine reductase
Molecular Weight
Mass (kDA):
36.02 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7q33 |
| Sequence: | 7; NC_000007.14 (134527567..134541412) |
Tissue Specificity
Found in many tissues. Highly expressed in small intestine, colon and adrenal gland.
Subcellular Localizations
Lysosome. Secreted. Secreted through a lysosome-mediated non-classical pathway.
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Malignant Neoplasm Of Lung
- Liver Carcinoma
- Adenocarcinoma
- Carcinogenesis
- Malignant Squamous Cell Neoplasm
- Non-small Cell Lung Carcinoma
- Liver Neoplasms
- Lung Neoplasms
- Malignant Neoplasm Of Liver
- Malignant Tumor Of Colon
Interacting Proteins
- ACACA
- TERF2IP
Pathways
- Cell Proliferation
- Drug Resistance
- Pathogenesis
- Cell Growth
- Cell Death
- Transport
- Keratinization
- Localization
- Reverse Transcription
- Cell Differentiation
- Gene Silencing
- Astrocyte Activation
- Prenylation
PTMs
- Reduction
- Oxidation
- Prenylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AKR1B10
bosterbio.com/bosterbio-gene-info-cards/AKR1B10
References
PMID: 9565553 by Cao D., et al. Identification and characterization of a novel human aldose reductase-like gene.
PMID: 9765596 by Hyndman D.J., et al. Sequence and expression levels in human tissues of a new member of the aldo-keto reductase family.
1 Publications of Boster AKR1B10 Antibodies & ELISA Kits
- PubMed ID: 10.18632/aging.103393, Loss of AKR1B10 promotes colorectal cancer cells proliferation and migration via...
*More publications can be found for each product on its corresponding product page