Annexin A4 Antibodies

Annexin A4 (ANXA4)

Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. .

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Gene Information

Human
Gene Name:	ANXA4
Uniprot:	P09525
Entrez:	307

Family

Belongs to:
annexin family

Alternative Names

AIV; Annexin A4; annexin IV (placental anticoagulant protein II); Annexin IV; annexin-4; ANX4; ANX4Carbohydrate-binding protein p33/p41; ANXA4; Chromobindin-4; chromobindin-4,35-beta calcimedin; DKFZp686H02120; Endonexin I; Lipocortin IV; MGC75105; P32.5; PAP-II; PIG28; Placental anticoagulant protein II; PP4-X; proliferation-inducing gene 28; proliferation-inducing protein 28; Protein II; ZAP36

Molecular Weight

Mass (kDA):
35.883 kDA

Genomic Context

Human
Location:	2p13.3
Sequence:	2; NC_000002.12 (69643808..69827112)

Diseases

• Malignant Neoplasms
• Neoplasms
• Endometrial Polyp
• Neoplasm Metastasis
• Carcinoma
• Malignant Paraganglionic Neoplasm
• Colorectal Neoplasms
• Endometrial Neoplasms
• Malignant Neoplasm Of Ovary
• Colorectal Cancer
• Cell Invasion
• Carcinoma, Endometrioid
• Cystadenocarcinoma, Serous

• Endometrial Carcinoma
• Stomach Neoplasms
• Malignant Neoplasm Of Breast
• Respiration Disorders
• Aneuploidy
• Neoplasm Invasiveness
• Intestinal Diseases

Interacting Proteins

• TINF2

Pathways

• Transport
• Translation
• Cell Death
• Cell Growth
• Cell Proliferation
• Programmed Cell Death
• Localization
• Coagulation
• Phagocytosis
• Water Transport
• Regulation Of Translation

• Exocytosis
• Response To Hydrostatic Pressure
• Epithelial Cell Proliferation
• Rna Interference
• Intestinal Cholesterol Absorption

PTMs

• Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ANXA4

Boster Bio - Best Uses Of The ANXA4 Marker

What is the difference between the ANXA4 and ANXA1 markers? Here are the differences between the two and how you can use them in your research. Using the right antibody is critical in identifying positive and negative samples in a research setting. Boster validates their antibodies on multiple platforms with known positive and negative samples. Moreover, Boster rewards the first reviewers of the product with product credits. Boster also rewards all scientists worldwide for the review of their products.

ANXA4

The ANXA4 marker provides scientists with a powerful tool for analyzing the genes of a specific species. This marker can also be used in research projects pertaining to specific species and applications. In addition, Boster scientists can submit results for species and application studies to get product credits. This tool can be used by scientists all over the world. This guide will discuss the best uses of this marker.

ANXA1

The ANXA4 gene is an important cellular protein that plays multiple roles. It supports calcium homeostasis and membrane transport. It has also shown promise as a potential anti-inflammatory drug. Zorn et al. have identified this gene's association with ovarian cancer and endometrial cancer. The gene is highly expressed in cancer cells, including hairy cell leukemia and lobular carcinoma of the breast.

ANXA2

High-affinity primary antibodies are a valuable resource in immunohistochemistry, western blotting, and ELISA experiments. Boster antibodies are widely cited in the research community and validated on Western Blotting, Immunohistochemistry, and ELISA. Boster bio offers a large portfolio of high-affinity primary antibodies to use in research projects. The antibodies used are highly specific and sensitive, allowing researchers to determine the presence of the protein of interest.

ANXA4 is an important transcription factor that influences the expression of target genes. In cells, ANXA4 influences the transcription of target genes associated with nuclear factor-k. These proteins include the nuclear factor-kB p50 and kB light-chain. At rest, NF-kB is kept in the cytoplasm by binding to the inhibitor of kB. This interaction may promote cell proliferation.

In experiments, ES-2 cells were transfected with pc-ANXA4-GFP plasmids or the equivalent Sh-ANXA4-GFP molecule. The transfection efficiency was determined by performing western blot analysis. Cells were then incubated with primary antibodies overnight at 4degC. Once a cell is transfected with an antibody, it can be further analyzed using immunohistochemical methods.

Moreover, Boster's gene infographics provide basic information about each gene. Gene infographics cover all mouse and human genes. You can easily find the gene you want to test using the gene search bar. You can also browse Boster's comprehensive database of gene information by typing it into the search bar. You will be presented with a list of gene-protein interactions.

While a limited number of studies have investigated the role of annexin A2, many studies have focused on the molecular mechanism of annexin A2 in the immune system. Although annexin A2 is primarily involved in the motility of epithelial cells, its role in tumor biology remains unclear. If the gene is expressed in tumors, this may be an indication of a tumor's sensitivity to chemotherapy.