Overview
| Product Name |
Anti-Annexin IV/ANXA4 Antibody
See all Annexin A4 primary antibodies, ELISA kits and proteins |
| SKU/Catalog Number |
PA1007-1 |
| Pack Size |
100μg/vial |
| Storage & Handling |
At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing. |
| Description |
Polyclonal antibody for Annexin A4/ANXA4 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Human. Annexin A4/ANXA4 information: Molecular Weight: 35883 MW; . |
| Cite This Product |
Anti-Annexin IV/ANXA4 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1007-1)
|
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Anti-Annexin IV/ANXA4 Antibody may replace the following items: sc 135831|sc 166762|sc 1924|sc 1930|sc 1930 R|sc 28827|sc 30760|sc 30761|sc 374254|sc 46693|sc 74438|sc 8300. |
Product Specs
| Host |
Rabbit |
| Reactivity/Species |
Human, Mouse, Rat |
| Predicted Reactivity |
Hamster
*This antibody is predicted to react with the above species based on antigen
sequence similarities. Our Boster Guarantee covers the use of this product with the above species. |
| Applications |
IHC, WB
*Our Boster Guarantee covers the use of this product in the above
tested applications.
*Innovating Scientists reward: if you test this antibody on a species or application not listed above and share with us your results, we will provide you a full credit to purchase Boster products. |
| Related Products |
Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).
*Blocking peptide can be purchased at $50. Contact us for more information.
**Boster also offers various secondary antibodies for Immunoflourescecne and IHC. Take advantage of the buy 1 primary antibody get 1 secondary antibody for free promotion all year round. |
| Immunogen |
A synthetic peptide corresponding to a sequence at the N-terminus of human Annexin IV(7-21aa TVKAASGFNAMEDAQ), different from the related mouse and rat sequences by one amino acid. |
| Cross Reactivity |
No cross reactivity with other proteins |
Gene/Protein Basic Information For ANXA4 (Source: Uniprot.org, NCBI)
| Uniprot Id | P09525 |
|---|
| NCBI Gene Id | 307 |
|---|
| Species Of This Entry | Human |
|---|
| Gene Name | ANXA4 |
|---|
| Protein Name | Annexin A4 |
|---|
| Superfamily | annexin family |
|---|
| Alternative Names | Annexin A4|AIV; Annexin A4; annexin IV (placental anticoagulant protein II); Annexin IV; annexin-4; ANX4; ANX4Carbohydrate-binding protein p33/p41; ANXA4; Chromobindin-4; chromobindin-4,35-beta calcimedin; DKFZp686H02120; Endonexin I; Lipocortin IV; MGC75105; P32.5; PAP-II; PIG28; Placental anticoagulant protein II; PP4-X; proliferation-inducing gene 28; proliferation-inducing protein 28; Protein II; ZAP36 |
|---|
| Molecular Weight | 35883 |
|---|
| Post Tranlational Modifications | Phosphorylation |
|---|
| Gene Location | 2p13.3, on Chromasome 2, gene sequence: NC_000002.12 (69643808..69827112) |
|---|
*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".
Ontology For ANXA4 (Source: Uniprot.org, NCBI)
| Protein Function | Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. . |
|---|
| Interacting Proteins | TINF2 |
|---|
| Related Diseases | Malignant Neoplasms; Neoplasms; Endometrial Polyp; Neoplasm Metastasis; Carcinoma; Malignant Paraganglionic Neoplasm; Colorectal Neoplasms; Endometrial Neoplasms; Malignant Neoplasm Of Ovary; Colorectal Cancer; Cell Invasion; Carcinoma, Endometrioid; Cystadenocarcinoma, Serous; Endometrial Carcinoma; Stomach Neoplasms; Malignant Neoplasm Of Breast; Respiration Disorders; Aneuploidy; Neoplasm Invasiveness; Intestinal Diseases |
|---|
| Related Pathways | Transport; Translation; Cell Death; Cell Growth; Cell Proliferation; Programmed Cell Death; Localization; Coagulation; Phagocytosis; Water Transport; Regulation Of Translation; Exocytosis; Response To Hydrostatic Pressure; Epithelial Cell Proliferation; Rna Interference; Intestinal Cholesterol Absorption |
|---|
| Background | Annexin IV, also known as placental anticoagulant protein II, or zymogen granule membrane-associated protein, 36-KD(ZAP36), is one of the family of calcium-dependent phospholipid-binding proteins whose normal function is uncertain. Annexin IV has 45 to 59% identity with other members of the annexin family. Annexin IV gene spans 18 to 56 kb. And it is located on mouse chromosome 6 in a region of conserved synteny with human chromosome 2. Rat annexin IV is ubiquitously expressed in epithelial tissues. Zap36 associated with zymogen granule membranes in dog and rat pancreas. Human annexin IV gene is mapped to chromosome 2p13. |
|---|
| Scientific References | PMID: 2970257 by Grundmann U., et al. Isolation and expression of cDNA coding for a new member of the phospholipase A2 inhibitor family.
PMID: 1346776 by Tait J.F., et al. Chromosomal mapping of the human annexin IV (ANX4) gene. |
|---|
Our Boster Quality Guarantee for Anti-Annexin IV/ANXA4 Antibody covers its use in the following applications.
Immunohistochemistry(Paraffin-embedded Section), 0.5-1μg/ml, Human, Rat, Mouse, By Heat
Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat
*The recommended dilution ratios/concentrations are for reference only and optimal dilutions/concentrations should be determined by the end user.
Anti-Annexin IV antibody, PA1007-1, IHC(P)
IHC(P): Human Mammary Cancer Tissue
Anti-Annexin IV antibody, PA1007-1, IHC(P)
IHC(P): Rat Pancreas Tissue
Anti-Annexin IV antibody, PA1007-1, Western blotting
Lane 1: Human Placenta Tissue Lysate
Lane 2: Rat Liver Tissue Lysate
Lane 3: 293T Cell Lysate
Lane 4: HEPA Cell Lysate
Lane 5: NIH3T3 Cell Lysate
Specific Protocols
Boster provides comprehensive technical information for WB, IHC/IF/ICC, Flow Cytometry sample preparation protocols, assay protocols, troubleshooting tips and assay optimization tips.
See all Annexin A4 primary antibodies,
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Total number of citations: 1
| Annexin A1, A2, A4 and A5 play important roles in breast cancer, pancreatic cancer and laryngeal carcinoma, alone and/or synergistically |
PubMed ID 30242262 |
