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- Table of Contents
Amyloid-like protein 1 Antibodies
AND APLP1 ELISA kits, Amyloid-like protein 1 Proteins
Many biological assays use antibodies to detect Amyloid-like protein 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Amyloid-like protein 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Amyloid-like protein 1 antibodies...
Designing a Western blot for Amyloid-like protein 1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the APLP1 Western Blot GuideAPLP1 Infographic by Boster Bio
All APLP1 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$499
Cat # FEK2103
96 wells/kit, with removable strips.
Cat # FEK2103
96 wells/kit, with removable strips.
Human, Mouse, Rat
Flow Cytometry, IHC, ICC, WB
$370
Cat # PB9476
100 μg/vial
Cat # PB9476
100 μg/vial
Human, Mouse, Rat
IHC, WB
$370
Cat # PA2096
100 μg/vial
Cat # PA2096
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A03929
100 µg/vial
Cat # A03929
100 µg/vial
APLP1 Overview
Facts about Amyloid-like protein 1.
Amyloid-like protein 1 (APLP1)
May play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding (By similarity).
Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways.
Gene Information
| Human | |
|---|---|
| Gene Name: | APLP1 |
| Uniprot: | P51693 |
| Entrez: | 333 |
Family
| Belongs to: |
|---|
| APP family |
Alternative Names
amyloid beta (A4) precursor-like protein 1; amyloid precursor-like protein 1; amyloid-like protein 1; APLP1; APLP-1; APLPAPLP-1
Molecular Weight
Mass (kDA):
72.176 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19q13.12 |
| Sequence: | 19; NC_000019.10 (35868445..35879797) |
Tissue Specificity
Expressed in the cerebral cortex where it is localized to the postsynaptic density (PSD).
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein.; [C30]: Cytoplasm. C-terminally processed in the Golgi complex.
Diseases
- Alzheimer's Disease
- Senile Plaques
- Tissue Adhesions
- Neuroblastoma
- Plaque, Amyloid
- Alzheimer Disease, Familial
- Neurotoxicity Syndromes
- Nerve Degeneration
- Nervousness
- Dementia
- Neurodegenerative Disorders
- Malnutrition
Interacting Proteins
- APLP2
- MED12
- ZNF24
Pathways
- Pathogenesis
- Proteolysis
- Secretion
- Transport
- Cell Adhesion
- Cell Death
- Aging
- Localization
- Cell Migration
- Brain Development
- Endocytosis
- Dna Repair
- Cell Cycle
PTMs
- Cleavage
- Phosphorylation
- Glycosylation
Research Areas
- Apoptosis
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/APLP1
bosterbio.com/bosterbio-gene-info-cards/APLP1
References
PMID: 9428684 by Paliga K., et al. Human amyloid precursor-like protein 1 -- cDNA cloning, ectopic expression in COS-7 cells and identification of soluble forms in the cerebrospinal fluid.
PMID: 9521588 by Lenkkeri U., et al. Structure of the human amyloid-precursor-like protein gene APLP1 at 19q13.1.