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Amyloid-like protein 1 Antibodies
AND APLP1 ELISA kits, Amyloid-like protein 1 Proteins
Many biological assays use antibodies to detect Amyloid-like protein 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Amyloid-like protein 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Amyloid-like protein 1 antibodies...
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APLP1 Infographic by Boster Bio
All APLP1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IHC, ICC, WB
$370
Cat # PB9476
100 μg/vial
Cat # PB9476
100 μg/vial
Human, Mouse, Rat
IHC, WB
$370
Cat # PA2096
100 μg/vial
Cat # PA2096
100 μg/vial
Human
ELISA
$750
Cat # EK2103
96 wells/kit, with removable strips.
Cat # EK2103
96 wells/kit, with removable strips.
Human
ELISA
$499
Cat # FEK2103
96 wells/kit, with removable strips.
Cat # FEK2103
96 wells/kit, with removable strips.
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A03929
100 µg/vial
Cat # A03929
100 µg/vial
APLP1 Overview
Facts about Amyloid-like protein 1.
Amyloid-like protein 1 (APLP1)
May play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding (By similarity).
Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways.
Gene Information
| Human | |
|---|---|
| Gene Name: | APLP1 |
| Uniprot: | P51693 |
| Entrez: | 333 |
Family
| Belongs to: |
|---|
| APP family |
Alternative Names
amyloid beta (A4) precursor-like protein 1; amyloid precursor-like protein 1; amyloid-like protein 1; APLP1; APLP-1; APLPAPLP-1
Molecular Weight
Mass (kDA):
72.176 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19q13.12 |
| Sequence: | 19; NC_000019.10 (35868445..35879797) |
Tissue Specificity
Expressed in the cerebral cortex where it is localized to the postsynaptic density (PSD).
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein.; [C30]: Cytoplasm. C-terminally processed in the Golgi complex.
Diseases
- Alzheimer's Disease
- Senile Plaques
- Tissue Adhesions
- Neuroblastoma
- Plaque, Amyloid
- Alzheimer Disease, Familial
- Neurotoxicity Syndromes
- Nerve Degeneration
- Nervousness
- Dementia
- Neurodegenerative Disorders
- Malnutrition
Interacting Proteins
- APLP2
- MED12
- ZNF24
Pathways
- Pathogenesis
- Proteolysis
- Secretion
- Transport
- Cell Adhesion
- Cell Death
- Aging
- Localization
- Cell Migration
- Brain Development
- Endocytosis
- Dna Repair
- Cell Cycle
PTMs
- Cleavage
- Phosphorylation
- Glycosylation
Research Areas
- Apoptosis
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/APLP1
bosterbio.com/bosterbio-gene-info-cards/APLP1
References
PMID: 9428684 by Paliga K., et al. Human amyloid precursor-like protein 1 -- cDNA cloning, ectopic expression in COS-7 cells and identification of soluble forms in the cerebrospinal fluid.
PMID: 9521588 by Lenkkeri U., et al. Structure of the human amyloid-precursor-like protein gene APLP1 at 19q13.1.