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Product Info Summary
| SKU: | PA2096 |
|---|---|
| Size: | 100 μg/vial |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | IHC, WB |
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Product info
Product Name
Anti-Amyloid-like protein 1 APLP1 Antibody
SKU/Catalog Number
PA2096
Size
100 μg/vial
Form
Lyophilized
Description
Boster Bio Anti-Amyloid-like protein 1 APLP1 Antibody catalog # PA2096. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Amyloid-like protein 1 APLP1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA2096)
Host
Rabbit
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human APLP1, different from the related mouse and rat sequences by two amino acids.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross-reactivity with other proteins
Reactive Species
PA2096 is reactive to APLP1 in Human, Mouse, Rat
Applications
PA2096 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
72 kDa
Calculated molecular weight
72.176kDa
Background of APLP-1
Amyloid-precursor-like protein 1 (APLP1) is a membrane-associated glycoprotein, whose gene is homologous to the APP gene, which has been shown to be involved in the pathogenesis of Alzheimer's disease. APLP1 is predominantly expressed in brain, particularly in the cerebral cortex postsynaptic density. The human gene has been mapped to chromosomal region 19q13.1. The gene is 11.8 kb long and contains 17 exons. APLP1 has been considered a candidate gene for CNF. All exon regions of the gene were amplified by the polymerase chain reaction and sequenced from DNA of CNF patients. No differences were observed between CNF patients and controls, suggesting that mutations in APLP1 are not involved in the etiology of CNF.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Reconsitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Rat, Mouse, By Heat
Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat
Validation Images & Assay Conditions
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Anti-APLP1 antibody, PA2096, IHC(P)
IHC(P): Human Lung Cancer Tissue
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Anti-APLP1 antibody, PA2096, Western blotting
All lanes: Anti APLP1 (PA2096) at 0.5ug/ml
Lane 1: HELA Whole Cell Lysate at 40ug
Lane 2: PC-12 Whole Cell Lysate at 40ug
Lane 3: HEPA Whole Cell Lysate at 40ug
Predicted bind size: 72KD
Observed bind size: 72KD
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Anti-APLP1 antibody, PA2096, IHC(P)
IHC(P): Rat Brain Tissue
Protein Target Info & Infographic
Gene/Protein Information For APLP1 (Source: Uniprot.org, NCBI)
Gene Name
APLP1
Full Name
Amyloid-like protein 1
Weight
72.176kDa
Superfamily
APP family
Alternative Names
amyloid beta (A4) precursor-like protein 1; amyloid precursor-like protein 1; amyloid-like protein 1; APLP1; APLP-1; APLPAPLP-1 APLP1 APLP amyloid beta precursor like protein 1 amyloid-like protein 1|amyloid beta (A4) precursor-like protein 1|amyloid precursor-like protein 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on APLP1, check out the APLP1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for APLP1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Amyloid-like protein 1 APLP1 Antibody (PA2096)
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No publications found for PA2096
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