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- Table of Contents
ATG13 Antibodies
AND ATG13 ELISA kits, ATG13 Proteins
Many biological assays use antibodies to detect ATG13, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ATG13 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ATG13 antibodies...
Designing a Western blot for ATG13? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the ATG13 Western Blot GuideATG13 Infographic by Boster Bio
All ATG13 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, IF, IHC-P, WB
$481
Cat # A02874
0.1 mg
Cat # A02874
0.1 mg
ATG13 Overview
Facts about Autophagy-related protein 13.
Autophagy-related protein 13 (ATG13)
Autophagy factor needed for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway which regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of this ATG13-ULK1- RB1CC1 complicated.
Throughout its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation. .
Gene Information
| Human | |
|---|---|
| Gene Name: | ATG13 |
| Uniprot: | O75143 |
| Entrez: | 9776 |
Family
| Belongs to: |
|---|
| ATG13 family |
Alternative Names
autophagy-related protein 13; autophagy related 13; KIAA0652
Molecular Weight
Mass (kDA):
56.572 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11p11.2 |
| Sequence: | 11; NC_000011.10 (46617276..46676019) |
Subcellular Localizations
Cytoplasm, cytosol. Preautophagosomal structure. Under starvation conditions, is localized to puncate structures primarily representing the isolation membrane; the isolation membrane sequesters a portion of the cytoplasm resulting in autophagosome formation.
Diseases
- Tissue Adhesions
- Neoplasms
- Sclerosis
- Waldenstrom Macroglobulinemia
- Nerve Degeneration
- Muscular Atrophy
- Monoclonal Gammapathies
- Monoclonal Gammopathy Of Undetermined Significance
- Feline Infectious Peritonitis And Pleuritis
Interacting Proteins
- ATG101
- GABARAP
- GABARAPL1
- GABARAPL2
- MAP1LC3B
- MAP1LC3C
- RB1CC1
- ULK1
Pathways
- Autophagy
- Macroautophagy
- Transport
- Localization
- Response To Nutrient
- Catabolic Process
- Cell Growth
- Cell Death
- Cvt Pathway
- Aging
- Regulation Of Autophagy
- Oogenesis
- Cell Proliferation
PTMs
- Phosphorylation
Research Areas
- Phospho-Specific
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ATG13
bosterbio.com/bosterbio-gene-info-cards/ATG13
References
PMID: 19597335 by Hosokawa N., et al. Atg101, a novel mammalian autophagy protein interacting with Atg13.
PMID: 19287211 by Mercer C.A., et al. A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy.