ATIC Antibodies

AND ATIC ELISA kits, ATIC Proteins

Many biological assays use antibodies to detect ATIC, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ATIC in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ATIC antibodies...

We validate the specificity of these antibodies to ATIC by testing them on tissues known to express ATIC positively and negatively. Browse below to find the ATIC antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ATIC Infographic by Boster Bio

All ATIC Products

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Product

Figures

Specificity

Applications

Price

Anti-ATIC Antibody

Western blot analysis of extracts of various cell lines, using ATIC antibody at 1:1000 dilution

Human

$405
Cat # A05404-1
100ul

Anti-ATIC monoclonal Antibody

Western blot detection of ATIC in various tissue and cell lysates using ATIC antibody (1:1000 diluted)

Human, Mouse, Rat

$482
Cat # M05404
100ul

Anti-ATIC Mouse Monoclonal Antibody [Clone ID: OTI1D2]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ATIC (Right lane) cDNA for 48 hrs and lysed

Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-ATIC monoclonal antibody

HEK293T cells transfected with either ATIC (Myc-DDK-tagged) overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-ATIC antibody (M05404-1)

Dog, Human, Monkey, Mouse, Rat

Flow Cytometry, WB

$523
Cat # M05404-1
100 µl

Anti-ATIC Antibody Picoband®

Western blot analysis of ATIC using anti-ATIC antibody (A05404-2)

Flow Cytometry analysis of K562 cells using anti-ATIC antibody (A05404-2)

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A05404-2
100 μg/vial

ATIC (NM_004044) Human Over-expression Lysate

Human

$628
Cat # LS000471
20 µg, 100 µg

ATIC Overview

Facts about Bifunctional purine biosynthesis protein PURH.

ATIC 3D structure. Source: alphafold

Bifunctional purine biosynthesis protein PURH (ATIC)

Bifunctional enzyme that catalyzes 2 measures in purine biosynthesis. .

Gene Information

Human
Gene Name:	ATIC
Uniprot:	P31939
Entrez:	471

Family

Belongs to:

PurH family

Alternative Names

5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMPcyclohydrolase; 5-aminoimidazole-4-carboxamide-1-beta-D-ribonucleotidetransformylase/inosinicase; AICAR formyltransferase/IMP cyclohydrolase bifunctional enzyme; AICAR; AICARFT; AICARFT/IMPCHASE; bifunctional purine biosynthesis protein PURH; IMPCHASE; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PURHFLJ93545

Molecular Weight

Mass (kDA):
64.616 kDA

Genomic Context


Human

Location:	2q35
Sequence:	2; NC_000002.12 (215311974..215359745)

Diseases

Arthritis
Rheumatoid Arthritis
Neoplasms
Lymphoma
Diffuse Large B-cell Lymphoma
Ki-1+ Anaplastic Large Cell Lymphoma
Anaplastic Lymphoma
5,10-methylenetetrahydrofolate Reductase Deficiency
Malignant Neoplasms
Chromosomal Translocation
Carcinoma
Kidney Diseases
Adenocarcinoma

Cardiovascular Diseases
Chronic Kidney Disease
T(2;5)(p23;q35)
Nervousness
Kidney Failure, Chronic
Cholangiocarcinoma
Hyperhomocysteinemia

Pathways

Response To Methotrexate
Pathogenesis
Transport
Cell Adhesion
Cell Division
Localization
Rna Interference

Glomerular Filtration
Excretion

PTMs

Phosphorylation

Cleavage

Dephosphorylation

Research Areas

Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ATIC

References

PMID: 8567683 by Rayl E.A., et al. The human purH gene product, 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. Cloning, sequencing, expression, purification, kinetic analysis, and domain mapping.

PMID: 8867801 by Yamauchi M., et al. Isolation of human purH gene expressed in the rodent transformant cells by subtractive enrichment of 3'-untranslated region of human transcript.