Anti-ATIC Antibody

ATIC antibody

Boster Bio Anti-ATIC Antibody catalog # A05404-1. Tested in WB applications. This antibody reacts with Human.

Product Info Summary

SKU: A05404-1
Size: 100ul
Reactive Species: Human
Host: Rabbit
Application: WB

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Product Name

Anti-ATIC Antibody

View all ATIC Antibodies

SKU/Catalog Number

A05404-1

Size

100ul

Form

Liquid

Description

Boster Bio Anti-ATIC Antibody catalog # A05404-1. Tested in WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-ATIC Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05404-1)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human CRSP77

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A05404-1 is reactive to ATIC in Human

Applications

A05404-1 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

111 kDa

Calculated molecular weight

64.616kDa

Background of ATIC

Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis.

Beebe S.J., Mol. Endocrinol. 4:465-475(1990).
Gregory S.G., Nature 441:315-321(2006).
Wu K.-J., Oncogene 21:7872-7882(2002).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:2000

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

Gene/Protein Information For ATIC (Source: Uniprot.org, NCBI)

Gene Name

ATIC

Full Name

Bifunctional purine biosynthesis protein PURH

Weight

64.616kDa

Superfamily

PurH family

Alternative Names

5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMPcyclohydrolase; 5-aminoimidazole-4-carboxamide-1-beta-D-ribonucleotidetransformylase/inosinicase; AICAR formyltransferase/IMP cyclohydrolase bifunctional enzyme; AICAR; AICARFT; AICARFT/IMPCHASE; bifunctional purine biosynthesis protein PURH; IMPCHASE; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PURHFLJ93545 ATIC AICAR, AICARFT, HEL-S-70p, IMPCHASE, PURH 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase bifunctional purine biosynthesis protein ATIC|5-aminoimidazole-4-carboxamide-1-beta-D-ribonucleotide transformylase/inosinicase|AICAR formyltransferase/IMP cyclohydrolase bifunctional enzyme|AICAR transformylase/inosine monophosphate cyclohydrolase|AICARFT/IMPCHASE|bifunctional purine biosynthesis protein PURH|epididymis secretory sperm binding protein Li 70p|phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on ATIC, check out the ATIC Infographic

ATIC infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for ATIC: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A05404-1-100ul

100ul

$405

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