Many biological assays use antibodies to detect CD27 antigen, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CD27 antigen in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CD27 antigen antibodies...
We validate the specificity of these antibodies to CD27 antigen by testing them on tissues known to express CD27 positively and negatively. Browse below to find the CD27 antibody that suites your experiment. We have 98 of these antibodies and many publications and validation images.
If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.
May play a role in apoptosis through association with SIVA1. .
Gene Information
Human
Gene Name:
CD27
Uniprot:
P26842
Entrez:
939
Family
Belongs to:
No superfamily
Alternative Names
CD27 antigen; CD27 molecule; CD27; MGC20393; S152CD27L receptor; T cell activation antigen CD27; T cell activation antigen S152; T14; TNFRSF7; TNFRSF7T-cell activation antigen CD27; Tp55; Tumor necrosis factor receptor superfamily member 7; tumor necrosis factor receptor superfamily, member 7
Molecular Weight
Mass (kDA): 29.137 kDA
Genomic Context
Human
Location:
12p13.31
Sequence:
12; NC_000012.12 (6444867..6451718)
Tissue Specificity
Found in most T-lymphocytes.
Subcellular Localizations
Membrane; Single-pass type I membrane protein.
Diseases
Neoplasms
Hiv Infections
Immunologic Deficiency Syndromes
Malignant Neoplasms
Leukemia
Lymphoma
Infective Disorder
Virus Diseases
Autoimmune Reaction
Inflammation
Cytomegalovirus Infections
Autoimmune Diseases
Malignant Paraganglionic Neoplasm
Lupus Erythematosus, Systemic
Arthritis
Tissue Adhesions
Lymphoid Leukemia
Influenza
Chronic Lymphocytic Leukemia
Rheumatoid Arthritis
Interacting Proteins
ACTN2
SIVA1
Pathways
Cell Activation
T Cell Activation
Immune Response
Secretion
Cell Differentiation
Cell Proliferation
Pathogenesis
Cytokine Production
T Cell Proliferation
Lymphocyte Activation
Cell Death
Cell Development
Cell Growth
Cell Cycle
T Cell Differentiation
Cytokine Secretion
B Cell Differentiation
B Cell Activation
Cell Maturation
Localization
PTMs
Phosphorylation
Cleavage
Glycosylation
Methylation
Biotinylation
Demethylation
Phosphorothioation
Gpi Anchoring
Ribosylation
Iodination
Reduction
Deglycosylation
Myristoylation
Research Areas
Apoptosis
Cancer
Immunology
Innate Immunity
For details, visit: bosterbio.com/bosterbio-gene-info-cards/CD27
References
PMID: 1655907 by Camerini D., et al. The T cell activation antigen CD27 is a member of the nerve growth factor/tumor necrosis factor receptor gene family.
PMID: 1334106 by Loenen W.A., et al. Genomic organization and chromosomal localization of the human CD27 gene.
11 Publications of Boster CD27 antigen Antibodies & ELISA Kits
PubMed ID: 10.1021/acsbiomaterials.0c01474, Synthesis of Double Interfering Biodegradable Nano-MgO Micelle Composites and Th...
PubMed ID: 10.1016/j.bbrc.2005.03.182, Inhibition of the PI3K pathway sensitizes fludarabine-induced apoptosis in human...
PubMed ID: 10.1007/s11302-015-9445-8, Up-regulation of P2X7 receptors mediating proliferation of Schwann cells after s...