Chromodomain-helicase-DNA-binding protein 2 (CHD2)

DNA-binding helicase that specifically binds to the promoter of target genes, leading to chromatin remodeling, possibly by encouraging deposition of histone H3.3.

Involved in myogenesis via interaction with MYOD1: binds to myogenic gene regulatory sequences and mediates incorporation of histone H3.3 prior to the beginning of myogenic gene expression, promoting their expression (By similarity).