CHD3 Antibodies

AND CHD3 ELISA kits, CHD3 Proteins

Many biological assays use antibodies to detect CHD3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CHD3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CHD3 antibodies...

We validate the specificity of these antibodies to CHD3 by testing them on tissues known to express CHD3 positively and negatively. Browse below to find the CHD3 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for CHD3? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the CHD3 IHC Guide

CHD3 Infographic by Boster Bio

All CHD3 Products

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Product

Figures

Specificity

Applications

Price

Anti-CHD3 Rabbit Monoclonal Antibody

Western blot analysis of CHD3 expression in K562 cell lysate

IHC analysis of CHD3 using anti-CHD3 antibody (M03200)

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M03200
100 μl/vial

Anti-CHD3 Rabbit Monoclonal Antibody

Western blot analysis of CHD3 expression in HeLa cell lysate

Human

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M03200-1
100 μl/vial

CHD3 (NM_001005273) Human Over-expression Lysate

Human

$960
Cat # LS001107
20 µg, 100 µg

CHD3 Overview

Facts about Chromodomain-helicase-DNA-binding protein 3.

CHD3 3D structure. Source: alphafold

Chromodomain-helicase-DNA-binding protein 3 (CHD3)

Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Required for anchoring centrosomal pericentrin in both interphase and mitosis, for spindle organization and centrosome integrity.

Gene Information

Human
Gene Name:	CHD3
Uniprot:	Q12873
Entrez:	1107

Family

Belongs to:

SNF2/RAD54 helicase family

Alternative Names

ATP-dependent helicase CHD3; CHD-3; chromodomain helicase DNA binding protein 3; chromodomain-helicase-DNA-binding protein 3; EC 3.6.1; EC 3.6.4.12; hZFH; Mi-2 autoantigen 240 kDa protein; Mi-2a; Mi2-ALPHA; ZFH; Zinc finger helicase; zinc-finger helicase (Snf2-like)

Molecular Weight

Mass (kDA):
226.592 kDA

Genomic Context


Human

Location:	17p13.1
Sequence:	17; NC_000017.11 (7884764..7912755)

Tissue Specificity

Widely expressed.

Subcellular Localizations

Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Associates with centrosomes in interphase and mitosis.

Diseases

Malignant Neoplasms
Neoplasms
Neuroblastoma
Alzheimer's Disease
Hypotension Adverse Event
Sclerosis
Stomach Neoplasms
Intraepithelial Neoplasia
Pediatric Neoplasm
Ataxia
Dermatomyositis
Bone Neoplasms

Coronary Artery Disease
Hypokinesia
Carcinoma
Leukemia, Myelocytic, Acute
Multiple Sclerosis, Relapsing-remitting
Osteosarcoma

Interacting Proteins

BARD1
DDX5
GIT1
HTT
KDM1A

PRPF40A
SERBP1
SUMO2
TRIM28
ZBTB7A

Pathways

Chromatin Remodeling
Germination
Methylation
Gene Silencing
Embryo Development
Histone Deacetylation
Cell Cycle
Dna Methylation
Localization
Pathogenesis
Cell Cycle Checkpoint
Shoot Development
Aging

Regulation Of Gene Expression
Histone Modification
Chromosome Segregation
Liver Development
Myelination
Double-strand Break Repair
Root Morphogenesis

PTMs

Methylation
Deacetylation
Phosphorylation

Cleavage
Sumoylation
Acetylation

Dephosphorylation

Research Areas

Immune Dysfunction
Immune System Diseases
Immunology

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CHD3

References

PMID: 9688266 by Aubry F., et al. Identification of a human 17p-located cDNA encoding a protein of the Snf2-like helicase family.

PMID: 9326634 by Woodage T., et al. Characterization of the CHD family of proteins.