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- Table of Contents
COL4A1 Antibodies
AND COL4A1 ELISA kits, COL4A1 Proteins
Many biological assays use antibodies to detect COL4A1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with COL4A1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop COL4A1 antibodies...
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COL4A1 Infographic by Boster Bio
All COL4A1 Products
Product
Figures
Specificity
Applications
Price
Anti-Collagen IV/COL4A1 Antibody Picoband®
23 Citations 16 Q&As
Human
IF, IHC, WB
$370
Cat # PB9099
100 μg/vial
Cat # PB9099
100 μg/vial
Anti-Collagen IV COL4A1 Antibody Picoband® (monoclonal, 3G3)
1 Citations 5 Q&As
Human
IF, IHC, WB
$370
Cat # M01411
100 μg/vial
Cat # M01411
100 μg/vial
Human, Mouse
ELISA
$480
Cat # EKC1128
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1128
1 kit, containing one 96-well plate and all necessary reagents
COL4A1 Overview
Facts about Collagen alpha-1(IV) chain.
Collagen alpha-1(IV) chain (COL4A1)
Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. .
Gene Information
| Human | |
|---|---|
| Gene Name: | COL4A1 |
| Uniprot: | P02462 |
| Entrez: | 1282 |
Family
| Belongs to: |
|---|
| type IV collagen family |
Alternative Names
alpha-1 chain; Arresten; COL4A1 NC1 domain; COL4A1; collagen alpha-1(IV) chain; Collagen IV alpha 1; collagen IV, alpha-1 polypeptide; collagen, type IV, alpha 1; Collagen-4; EC 3.4.23; EC 6.3.1.2
Molecular Weight
Mass (kDA):
160.611 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 13q34 |
| Sequence: | 13; NC_000013.11 (110148963..110307157, complement) |
Tissue Specificity
Highly expressed in placenta.
Subcellular Localizations
Secreted, extracellular space, extracellular matrix, basement membrane.
Diseases
- Hemorrhage
- Cerebral Hemorrhage
- Acquired Porencephaly
- Kidney Diseases
- Cerebrovascular Accident
- Leukoencephalopathies
- Fibrosis
- Aneurysm
- Tissue Adhesions
- Hereditary Nephritis
- Brain Diseases
- Intracranial Aneurysm
- Muscle Cramp
Interacting Proteins
- COL4A2
Pathways
- Pathogenesis
- Cell Proliferation
- Secretion
- Angiogenesis
- Localization
- Excretion
- Cell Adhesion
- Tissue Development
- Reverse Transcription
- Translation
- Wound Healing
- Coagulation
- Cell Death
PTMs
- Cleavage
Research Areas
- Cell Biology
- Cellular Markers
- Extracellular Matrix
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/COL4A1
bosterbio.com/bosterbio-gene-info-cards/COL4A1
References
PMID: 2701944 by Soininen R., et al. Structural organization of the gene for the alpha 1 chain of human type IV collagen.
PMID: 3311751 by Brazel D., et al. Completion of the amino acid sequence of the alpha 1 chain of human basement membrane collagen (type IV) reveals 21 non-triplet interruptions located within the collagenous domain.
52 Publications of Boster COL4A1 Antibodies & ELISA Kits
- PubMed ID: PMID:16191423, Protective effects of blocking renin-angiotensin system on the progression of re...
- PubMed ID: 10.3892/etm.2016.3218, Protective effects of Danggui Buxue Tang on renal function, renal glomerular mes...
- PubMed ID: 10.3390/nu8050276, Sesamin Ameliorates High-Fat Diet–Induced Dyslipidemia and Kidney Injury by Re...
- PubMed ID: 10.3109/10799893.2016.1155068, Neutral endopeptidase and natriuretic peptide receptors participate in the regul...
- PubMed ID: 10.3109/0886022X.2014.934694, Effects of uPA on mesangial matrix changes in the kidney of diabetic rats
- PubMed ID: 10.1590/S0100-879X2010007500132, The effect of down-regulation of Smad3 by RNAi on hepatic stellate cells and a c...
- PubMed ID: 10.1538/expanim.56.11, Severe Insulin Resistance and Moderate Glomerulosclerosis in a Minipig Model Ind...
- PubMed ID: 10.1093/toxsci/kfm010, Rosiglitazone Prevents Advanced Glycation End Products–Induced Renal Toxicity ...
- PubMed ID: 10.1016/S0002-9440(10)63254-3, Advanced Glycation End-Products Induce Connective Tissue Growth Factor-Mediated ...
- PubMed ID: 10.1016/j.phymed.2017.09.001, Cardioprotection of Sheng Mai Yin a classic formula on adriamycin induced myocar...
- PubMed ID: 10.1016/j.biopha.2020.110321, Ibrolipim attenuates early-stage nephropathy in diet-induced diabetic minipigs: ...
- PubMed ID: 10.1007/s12020-010-9419-0, Effects of aminoguanidine and vitamin C on collagen type IV in diabetic nephropa...
- PubMed ID: 10.1007/s11095-013-1209-y, Electrosprayed Microparticles with Loaded pDNA-Calcium Phosphate Nanoparticles t...
- PubMed ID: 10.1007/s11033-012-2321-5, Renoprotective effects of berberine and its possible molecular mechanisms in com...
- PubMed ID: -, Yu WY,Cai W,Ying HZ, Zhang WY,Zhang HH,Yu CH.Exogenous Plant gma-miR-159a, Ident...
- PubMed ID: -, Yang, Y., Deng, R., Chen, Z., Yao, L., Yang, X., & Xiang, D. (2021). Piperazine ...
- PubMed ID: 33581205, Lian Y,Zhu M,Chen J,Yang B,Lv Q,Wang L,Guo S,Tan X,Li C,Bu W,Ding W,Jia X,Feng L...
- PubMed ID: 32475419, Zhou S,Ma Y,Zhao D,Mi Y,Zhang C. Transcriptome profiling analysis of underlying ...
- PubMed ID: 28656209, Hydrogen sulfide reduced renal tissue fibrosis by regulating autophagy in diabet...
- PubMed ID: 28627680, BMP-7 suppresses excessive scar formation by activating the BMP-7/Smad1/5/8 sign...
- PubMed ID: 28260896, Long-term intravenous administration of carboxylated single-walled carbon nanotu...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page