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- Table of Contents
Carboxypeptidase B2 Antibodies
AND CPB2 ELISA kits, Carboxypeptidase B2 Proteins
Many biological assays use antibodies to detect Carboxypeptidase B2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Carboxypeptidase B2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Carboxypeptidase B2 antibodies...
Designing a Western blot for Carboxypeptidase B2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CPB2 Western Blot GuideCPB2 Infographic by Boster Bio
All CPB2 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$500
Cat # EZ1502
For 5 plates, 96 wells each
Cat # EZ1502
For 5 plates, 96 wells each
Human
ELISA
$499
Cat # EK1502
96 wells/kit, with removable strips.
Cat # EK1502
96 wells/kit, with removable strips.
Human
IHC, WB, ELISA (Cap)
$370
Cat # PB9997
100 μg/vial
Cat # PB9997
100 μg/vial
Human
$628
Cat # LS001361
20 µg, 100 µg
Cat # LS001361
20 µg, 100 µg
Human
IHC
$523
Cat # M02532
100 µl
Cat # M02532
100 µl
CPB2 Overview
Facts about Carboxypeptidase B2.
Carboxypeptidase B2 (CPB2)
Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins from the circulation thereby regulating their activities. Down- regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | CPB2 |
| Uniprot: | Q96IY4 |
| Entrez: | 1361 |
Family
| Belongs to: |
|---|
| peptidase M14 family |
Alternative Names
carboxypeptidase B2 (plasma); carboxypeptidase B2 (plasma, carboxypeptidase U); Carboxypeptidase B2; Carboxypeptidase U; CPB2; CPU; CPUEC 3.4.17.20; EC 3.4.17; PCPB; Plasma carboxypeptidase B; TAFI; TAFIcarboxypeptidase B-like protein; Thrombin-activable fibrinolysis inhibitor; thrombin-activatable fibrinolysis inhibitor
Molecular Weight
Mass (kDA):
48.424 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 13q14.13 |
| Sequence: | 13; NC_000013.11 (46053066..46105076, complement) |
Tissue Specificity
Plasma; synthesized in the liver.
Subcellular Localizations
Secreted.
Diseases
- Clostridium Infections
- Enteritis
- Diarrhea
- Swine Diseases
- Poultry Diseases
- Enterotoxemia
- Infective Disorder
- Food Poisoning
- Inflammation
- Poisoning
- Ulcer
- Gastrointestinal Diseases
Pathways
- Virulence
- Fibrinolysis
- Pathogenesis
- Coagulation
- Locomotor Rhythm
- Swimming
- Locomotion
- Transport
- Glycosylation
- Immune Response
- Commensalism
- Autolysis
- Glomerular Filtration
PTMs
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CPB2
bosterbio.com/bosterbio-gene-info-cards/CPB2
References
PMID: 1939207 by Eaton D.L., et al. Isolation, molecular cloning, and partial characterization of a novel carboxypeptidase B from human plasma.
PMID: 10574983 by Mao S.S., et al. Characterization of plasmin-mediated activation of plasma procarboxypeptidase B. Modulation by glycosaminoglycans.
1 Publications of Boster Carboxypeptidase B2 Antibodies & ELISA Kits
- PubMed ID: 19018804, INVOLVEMENT OF PROLYLCARBOXYPEPTIDASE IN THE EFFECT OF RUTAECARPINE ON THE REGRE...
*More publications can be found for each product on its corresponding product page