Anti-Carboxypeptidase B2/CPB2 Antibody Picoband™

Carboxypeptidase B2/CPB2 antibody

Boster Bio Anti-Carboxypeptidase B2/CPB2 Antibody Picoband™ catalog # PB9998. Tested in WB applications. This antibody reacts with Mouse. Cited in 1 publication(s).

Product Info Summary

SKU: PB9998
Size: 100 μg/vial
Reactive Species: Mouse
Host: Rabbit
Application: WB

Product Name

Anti-Carboxypeptidase B2/CPB2 Antibody Picoband™

View all Carboxypeptidase B2/CPB2 Antibodies

SKU/Catalog Number

PB9998

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Carboxypeptidase B2/CPB2 Antibody Picoband™ catalog # PB9998. Tested in WB applications. This antibody reacts with Mouse.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Carboxypeptidase B2/CPB2 Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # PB9998)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E. coli-derived mouse CPB2 recombinant protein (Position: K165-D387). Mouse CPB2 shares 86.1% and 96.9% amino acid (aa) sequence identity with human and rat CPB2, respectively.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PB9998 is reactive to CPB2 in Mouse

Applications

PB9998 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

48 kDa

Calculated molecular weight

48.424kDa

Background of Carboxypeptidase B2/CPB2

Carboxypeptidase B2 (CPB2), also known as carboxypeptidase U (CPU), plasma carboxypeptidase B (pCPB) or thrombin-activatable fibrinolysis inhibitor (TAFI), is an enzyme that, in humans, is encoded by the gene CPB2. CPB2 is synthesized by the liver and circulates in the plasma as a plasminogen-bound zymogen. When it is activated by proteolysis at residue Arg92 by the thrombin/thrombomodulin complex, CPB2 exhibits carboxypeptidase activity. Activated CPB2 reduces fibrinolysis by removing the fibrin C-terminal residues that are important for the binding and activation of plasminogen.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Mouse

Validation Images & Assay Conditions

Gene/Protein Information For CPB2 (Source: Uniprot.org, NCBI)

Gene Name

CPB2

Full Name

Carboxypeptidase B2

Weight

48.424kDa

Superfamily

peptidase M14 family

Alternative Names

carboxypeptidase B2 (plasma); carboxypeptidase B2 (plasma, carboxypeptidase U); Carboxypeptidase B2; Carboxypeptidase U; CPB2; CPU; CPUEC 3.4.17.20; EC 3.4.17; PCPB; Plasma carboxypeptidase B; TAFI; TAFIcarboxypeptidase B-like protein; Thrombin-activable fibrinolysis inhibitor; thrombin-activatable fibrinolysis inhibitor CPB2 CPU, PCPB, TAFI carboxypeptidase B2 carboxypeptidase B2|carboxypeptidase B-like protein|carboxypeptidase B2 (plasma)|carboxypeptidase B2 (plasma, carboxypeptidase U)|carboxypeptidase R|thrombin-activable fibrinolysis inhibitor|thrombin-activatable fibrinolysis inhibitor

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on CPB2, check out the CPB2 Infographic

CPB2 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for CPB2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

PB9998 has been cited in 1 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

INVOLVEMENT OF PROLYLCARBOXYPEPTIDASE IN THE EFFECT OF RUTAECARPINE ON THE REGRESSION OF MESENTERIC ARTERY HYPERTROPHY IN RENOVASCULAR HYPERTENSIVE RATS

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1 Customer Q&As for Anti-Carboxypeptidase B2/CPB2 Antibody Picoband™

Question

We are currently using anti-Carboxypeptidase B2/CPB2 antibody PB9998 for mouse tissue, and we are satisfied with the WB results. The species of reactivity given in the datasheet says mouse. Is it true that the antibody can work on dog tissues as well?

Verified Customer

Verified customer

Asked: 2019-07-26

Answer

The anti-Carboxypeptidase B2/CPB2 antibody (PB9998) has not been tested for cross reactivity specifically with dog tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in dog you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2019-07-26

Order DetailsPrice
PB9998

100μg

$370
PB9998-10ug

10μg sample (liquid)

$99
PB9998-Biotin

100 μg Biotin conjugated

$570
PB9998-Cy3

100 μg Cy3 conjugated

$570
PB9998-Dylight488

100 μg Dylight488 conjugated

$570
PB9998-Dylight550

100 μg Dylight550 conjugated

$570
PB9998-Dylight594

100 μg Dylight594 conjugated

$570
PB9998-FITC

100 μg FITC conjugated

$570
PB9998-HRP

100 μg HRP conjugated

$570
PB9998-APC

100 μg APC conjugated

$670
PB9998-PE

100 μg PE conjugated

$670
PB9998-carrier-free

Carrier Free

$370

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Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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