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- Table of Contents
Corticoliberin Antibodies
AND CRH ELISA kits, Corticoliberin Proteins
Many biological assays use antibodies to detect Corticoliberin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Corticoliberin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Corticoliberin antibodies...
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CRH Infographic by Boster Bio
All CRH Products
Product
Figures
Specificity
Applications
Price
Human
$628
Cat # LS001392
20 µg, 100 µg
Cat # LS001392
20 µg, 100 µg
CRH Overview
Facts about Corticoliberin.
Corticoliberin (CRH)
Hormone regulating the release of corticotropin from pituitary gland (By similarity). Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile (By similarity).
.
Gene Information
| Human | |
|---|---|
| Gene Name: | CRH |
| Uniprot: | P06850 |
| Entrez: | 1392 |
Family
| Belongs to: |
|---|
| sauvagine/corticotropin-releasing factor/urotensin I family |
Alternative Names
CRF; CRH; ProCorticoliberin; Pro-Corticoliberin
Molecular Weight
Mass (kDA):
21.422 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 8q13.1 |
| Sequence: | 8; NC_000008.11 (66176376..66178464, complement) |
Tissue Specificity
Produced by the hypothalamus and placenta.
Subcellular Localizations
Secreted.
Diseases
- Pituitary Diseases
- Depressive Disorder
- Physiological Stress
- Cushing Syndrome
- Stress, Psychological
- Neoplasms
- Anxiety Disorders
- Nervousness
- Pituitary-dependent Cushing's Disease
- Adenoma
- Major Depressive Disorder
- Pituitary Neoplasms
Interacting Proteins
- CRHR1
- KRT31
Pathways
- Secretion
- Cortisol Secretion
- Response To Stress
- Hormone Secretion
- Pathogenesis
- Parturition
- Localization
- Excretion
- Corticosterone Secretion
- Aging
- Circadian Rhythm
- Transport
- Innervation
PTMs
- Phosphorylation
- Cleavage
- Methylation
- Reduction
- Oxidation
- Dephosphorylation
- Glycosylation
- Acetylation
- Biotinylation
- Phosphorothioation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CRH
bosterbio.com/bosterbio-gene-info-cards/CRH
References
PMID: 6605851 by Shibahara S., et al. Isolation and sequence analysis of the human corticotropin-releasing factor precursor gene.
PMID: 2783917 by Robinson B.G., et al. Preprocorticotropin releasing hormone: cDNA sequence and in vitro processing.