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- Table of Contents
5 Citations 8 Q&As
2 Citations 10 Q&As
1 Citations
Facts about C-X-C motif chemokine 16.
Induces calcium mobilization. Binds to CXCR6/Bonzo.
| Human | |
|---|---|
| Gene Name: | CXCL16 |
| Uniprot: | Q9H2A7 |
| Entrez: | 58191 |

| Belongs to: |
|---|
| intercrine alpha (chemokine CxC) family |

chemokine (C-X-C motif) ligand 16; CXC chemokine ligand 16; CXCL16; CXCLG16; Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein; SCYB16; Small-inducible cytokine B16; SRPSOXC-X-C motif chemokine 16; SR-PSOXTransmembrane chemokine CXCL16
Mass (kDA):
27.579 kDA

| Human | |
|---|---|
| Location: | 17p13.2 |
| Sequence: | 17; NC_000017.11 (4733533..4739928, complement) |
Expressed in T-cell areas. Expressed in spleen, lymph nodes, lung, kidney, small intestine and thymus. Weak expression in heart and liver and no expression in brain and bone marrow.
Cell membrane; Single-pass type I membrane protein. Secreted. Also exists as a soluble form.




PMID: 11017100 by Matloubian M., et al. A transmembrane CXC chemokine is a ligand for HIV-coreceptor Bonzo.
PMID: 11290797 by Wilbanks A., et al. Expression cloning of the strl33/bonzo/tymstr ligand reveals elements of cc, cxc, and cx3c chemokines.
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