This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Cytochrome P450 1A1 Antibodies
AND CYP1A1 ELISA kits, Cytochrome P450 1A1 Proteins
Many biological assays use antibodies to detect Cytochrome P450 1A1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cytochrome P450 1A1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cytochrome P450 1A1 antibodies...
Designing an IHC experiment for Cytochrome P450 1A1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the CYP1A1 IHC GuideCYP1A1 Infographic by Boster Bio
All CYP1A1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, IHC-F, ICC, WB
$370
Cat # PB9544
100 μg/vial
Cat # PB9544
100 μg/vial
CYP1A1 Overview
Facts about Cytochrome P450 1A1.
Cytochrome P450 1A1 (CYP1A1)
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway.
It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CYP1A1 |
| Uniprot: | P04798 |
| Entrez: | 1543 |
Family
| Belongs to: |
|---|
| cytochrome P450 family |
Alternative Names
AHH; AHRR; aryl hydrocarbon hydroxylase; CP11; CYP1; CYPIA1; cytochrome P1-450, dioxin-inducible; cytochrome P450 1A1; Cytochrome P450 form 6; cytochrome P450, family 1, subfamily A, polypeptide 1; Cytochrome P450-C; Cytochrome P450-P1; EC 1.14.14.1; flavoprotein-linked monooxygenase; P1-450; P450-C; P450DX; subfamily I (aromatic compound-inducible), polypeptide 1; xenobiotic monooxygenase
Molecular Weight
Mass (kDA):
58.165 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 15q24.1 |
| Sequence: | 15; NC_000015.10 (74719542..74725528, complement) |
Tissue Specificity
Lung, lymphocytes and placenta.
Subcellular Localizations
Endoplasmic reticulum membrane; Peripheral membrane protein. Mitochondrion inner membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. Cytoplasm.
Diseases
- Malignant Neoplasms
- Neoplasms
- Liver Carcinoma
- Carcinogenesis
- Carcinoma
- Malignant Neoplasm Of Breast
- Malignant Neoplasm Of Lung
- Mammary Neoplasms
- Lung Neoplasms
- Malignant Squamous Cell Neoplasm
- Adenocarcinoma
- Liver Neoplasms
Interacting Proteins
- CMTM5
Pathways
- Cell Cycle
- Cell Proliferation
- Localization
- Pathogenesis
- Dna Repair
- Conjugation
- Excretion
- Transport
- Cell Growth
- Secretion
- Methylation
- Cell Death
- Demethylation
PTMs
- Hydroxylation
- Oxidation
- Demethylation
- Phosphorylation
- Methylation
- Acetylation
- Reduction
- Cleavage
- Bromination
- Ubiquitination
Research Areas
- Breast Cancer
- Lipid and Metabolism
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CYP1A1
bosterbio.com/bosterbio-gene-info-cards/CYP1A1
References
PMID: 2989797 by Jaiswal A.K., et al. Human P1-450 gene sequence and correlation of mRNA with genetic differences in benzo[a]pyrene metabolism.
PMID: 3838385 by Jaiswal A.K., et al. Human dioxin-inducible cytochrome P1-450: complementary DNA and amino acid sequence.
1 Publications of Boster Cytochrome P450 1A1 Antibodies & ELISA Kits
- PubMed ID: 30942466 , Prenatal nicotine exposure induces depression‑like behavior in adolescent fema...
*More publications can be found for each product on its corresponding product page