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- Table of Contents
DFFA Antibodies
AND DFFA ELISA kits, DFFA Proteins
Many biological assays use antibodies to detect DFFA, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DFFA in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DFFA antibodies...
Designing a Western blot for DFFA? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the DFFA Western Blot GuideDFFA Infographic by Boster Bio
All DFFA Products
Product
Figures
Specificity
Applications
Price
Human, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A03671-4
100 μg/vial
Cat # A03671-4
100 μg/vial
Human
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M03671-1
100 μl/vial
Cat # M03671-1
100 μl/vial
DFFA Overview
Facts about DNA fragmentation factor subunit alpha.
DNA fragmentation factor subunit alpha (DFFA)
Inhibitor of the caspase-activated DNase (DFF40).
.Gene Information
| Human | |
|---|---|
| Gene Name: | DFFA |
| Uniprot: | O00273 |
| Entrez: | 1676 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
DFF1; DFF1DNA fragmentation factor 45 kDa subunit; DFF45; DFF45DNA fragmentation factor subunit alpha; DFF-45DNA fragmentation factor, 45 kD, alpha polypeptide; DFFA; DNA fragmentation factor, 45kDa, alpha polypeptide; ICAD; Inhibitor of CAD
Molecular Weight
Mass (kDA):
36.522 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p36.22 |
| Sequence: | 1; NC_000001.11 (10456522..10472529, complement) |
Subcellular Localizations
Cytoplasm.
Diseases
- Neoplasms
- Neuroblastoma
- Obesity
- Diabetes Mellitus
- Carcinoma
- Malignant Neoplasms
- Steatohepatitis
- Steatosis
- Hypoxia
- Hepatic Ischaemia
- Neoplasms, Germ Cell And Embryonal
- Malignant Tumor Of Cervix
Interacting Proteins
- DFFB
- Dffb
- HSPB1
Pathways
- Cell Proliferation
- Cell Death
- Fatty Acid Oxidation
- Programmed Cell Death
- Gene Silencing
- Fertilization
- Proteolysis
- Glycosylation
- Insemination
- Localization
- Methylation
- Apoptotic Dna Fragmentation
PTMs
- Cleavage
- Oxidation
Research Areas
- Apoptosis
- Cancer
- Cell Biology
- Cell Cycle and Replication
- Tumor Suppressors
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DFFA
bosterbio.com/bosterbio-gene-info-cards/DFFA
References
PMID: 9108473 by Liu X., et al. DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis.
PMID: 10409614 by Gu J.J., et al. Functional interaction of DFF35 and DFF45 with caspase-activated DNA fragmentation nuclease DFF40.