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- Table of Contents
Facts about DNA fragmentation factor subunit alpha.
Inhibitor of the caspase-activated DNase (DFF40).
.Human | |
---|---|
Gene Name: | DFFA |
Uniprot: | O00273 |
Entrez: | 1676 |
Belongs to: |
---|
No superfamily |
DFF1; DFF1DNA fragmentation factor 45 kDa subunit; DFF45; DFF45DNA fragmentation factor subunit alpha; DFF-45DNA fragmentation factor, 45 kD, alpha polypeptide; DFFA; DNA fragmentation factor, 45kDa, alpha polypeptide; ICAD; Inhibitor of CAD
Mass (kDA):
36.522 kDA
Human | |
---|---|
Location: | 1p36.22 |
Sequence: | 1; NC_000001.11 (10456522..10472529, complement) |
Cytoplasm.
This article will explain the benefits of the DFFA marker from Boster Bio. You will also learn about its application and the detection techniques. Once you have a grasp of the DFFA Marker, you will be well on your way to creating a powerful bioanalyst. These are some tips to help make this powerful tool even more accessible.
Boster Bio Antibodies for DFFA/ICAD are available in catalog # A03671-4. The antibodies react with Rat and Human samples. They can be stored at -20°C for one year. They are highly purified with 4mg Trehalose. A blocking peptide also exists for DFFA/ICAD recombinant peptides. This guide can help you optimize your experiments.
Follow the guidelines outlined on page 5 for full requirements to apply as a DFFA Marker. A detailed description is required to support the marker's location and text. Photos and descriptions need to be high quality, and labeled clearly with the date of the photograph and the property name. It is also useful to have directions. For more information, visit the DFFA's website. The application can be downloaded by clicking here.
Within five business days, completed applications will be processed by the Michigan History Center and sent to it. Incomplete applications will not be accepted. The Michigan History Center then contacts the applicant by mail to confirm receipt of application materials. Once approved, the applicant must submit primary source documentation for the marker. The fee for the marker is $250 Applications must be received by March 1 to be considered. If the marker is not approved, the fee is refundable.
PMID: 9108473 by Liu X., et al. DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis.
PMID: 10409614 by Gu J.J., et al. Functional interaction of DFF35 and DFF45 with caspase-activated DNA fragmentation nuclease DFF40.