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- Table of Contents
Glucagon Antibodies
AND GCG ELISA kits, Glucagon Proteins
Many biological assays use antibodies to detect Glucagon, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Glucagon in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Glucagon antibodies...
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GCG Infographic by Boster Bio
All GCG Products
Product
Figures
Specificity
Applications
Price
Anti-Glucagon Gcg Antibody (Monoclonal, K79bB10)
19 Citations 5 Q&As
Human, Mouse, Rabbit, Rat
IF, IHC
$370
Cat # MA1047
100 μg/vial
Cat # MA1047
100 μg/vial
Anti-Glucagon GCG Rabbit Monoclonal Antibody
1 Citations
Human, Mouse, Rat
IHC, WB
$370
Cat # M00678
100 μl
Cat # M00678
100 μl
Human, Mouse, Rat
ELISA
$480
Cat # EKC1240
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1240
1 kit, containing one 96-well plate and all necessary reagents
GCG Overview
Facts about Glucagon.
Glucagon (GCG)
Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis.
A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating and maintaining hyperglycemic conditions in diabetes.
Gene Information
| Human | |
|---|---|
| Gene Name: | GCG |
| Uniprot: | P01275 |
| Entrez: | 2641 |
Family
| Belongs to: |
|---|
| glucagon family |
Alternative Names
GCG; glicentin-related polypeptide; GLP1; GLP-1; Glucagon; glucagon-like peptide 1; glucagon-like peptide 2; GRPP
Molecular Weight
Mass (kDA):
20.909 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q24.2 |
| Sequence: | 2; NC_000002.12 (162142882..162152247, complement) |
Tissue Specificity
Glucagon is secreted in the A cells of the islets of Langerhans. GLP-1, GLP-2, oxyntomodulin and glicentin are secreted from enteroendocrine cells throughout the gastrointestinal tract. GLP-1 and GLP-2 are also secreted in selected neurons in the brain.
Subcellular Localizations
Secreted.
Diseases
- Diabetes Mellitus, Non-insulin-dependent
- Diabetes Mellitus
- Metabolic Diseases
- Obesity
- Impaired Glucose Tolerance
- Hyperplasia
- Glucagon Deficiency
- Nervous System Disorder
- Diphtheria
- Haploinsufficiency
Interacting Proteins
- DPP4
- FAP
- GIPR
Pathways
- Secretion
- Insulin Secretion
- Reverse Transcription
- Cell Proliferation
- Gluconeogenesis
- Glucagon Secretion
- Response To Camp
- Glucose Homeostasis
- Dna Replication
- Hormone Secretion
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GCG
bosterbio.com/bosterbio-gene-info-cards/GCG
References
PMID: 2901414 by Drucker D.J., et al. Glucagon gene expression in vertebrate brain.
PMID: 3725587 by White J.W., et al. Structure of the human glucagon gene.
12 Publications of Boster Glucagon Antibodies & ELISA Kits
- PubMed ID: 32328034, Huo K,Li X,Hu W,Song X,Zhang D,Zhang X,Chen X,Yuan J,Zuo J,Wang X.RFRP-3, the Ma...
- PubMed ID: 27721485, The anti-hyperglycemic efficacy of a lipid-lowering drug Daming capsule and the ...
- PubMed ID: 29950431, Generation and Phenotype Identification of PAX4 Gene Knockout Rabbit by CRISPR/C...
- PubMed ID: 29942142, Chronic oscillating glucose challenges disarrange innate immune homeostasis to p...
- PubMed ID: 29089617, Low dose doxycycline decreases systemic inflammation and improves glycemic contr...
- PubMed ID: 20504302, Chen Ll, Yang Wh, Zheng J, Hu X, Kong W, Zhang Hh. Nutr Metab (Lond). 2010 May 2...
- PubMed ID: 21956205, Lan F, Yue X, Han L, Shi Z, Yang Y, Pu P, Yao Z, Kang C. Int J Oncol. 2012 Feb;4...
- PubMed ID: 21667819, Jiang H, Deng Xf, Duan Cm, Chen C, Xiang Jl, Lu Yl, Ma Qf. Lymphology. 2011 Mar;...
- PubMed ID: 23762850, Zhang Y, Ye C, Wang G, Gao Y, Tan K, Zhuo Z, Liu Z, Xia H, Yang D, Li P. Biomed ...
- PubMed ID: 19788384, Zhang W, Jin H, Hu Y, Yu Y, Li X, Ding Z, Kang Y, Wang B. Hum Gene Ther. 2010 Fe...
- PubMed ID: 25675848, Liu Jj, Raynal S, Bailb?? D, Gausseres B, Carbonne C, Autier V, Movassat J, Kerg...
- PubMed ID: 20842108, Tang Mm, Zhu Qe, Fan Wz, Zhang Sl, Li Dz, Liu Lz, Chen M, Zhang M, Zhou J, Wei C...
*More publications can be found for each product on its corresponding product page