Many biological assays use antibodies to detect HLA-A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HLA-A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HLA-A antibodies...
We validate the specificity of these antibodies to HLA-A by testing them on tissues known to express HLA-A positively and negatively. Browse below to find the HLA-A antibody that suites your experiment. We have 77 of these antibodies and many publications and validation images.
If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.
Facts about HLA class I histocompatibility antigen, A alpha chain.
HLA class I histocompatibility antigen, A alpha chain (HLA-A)
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Gene Information
Human
Gene Name:
HLA-A
Uniprot:
P01891
Entrez:
3105
Family
Belongs to:
MHC class I family
Alternative Names
A-10 alpha chain; FLJ26655; HLA class I histocompatibility antigen, A-1 alpha chain; HLA class I histocompatibility antigen, A-28 alpha chain; HLA class I histocompatibility antigen, A-9 alpha chain; HLAA; major histocompatibility complex, class I, A; MHC class I antigen A*1; MHC class I antigen A*11; MHC class I antigen A*80
Molecular Weight
Mass (kDA): 40.841 kDA
Genomic Context
Human
Location:
6p22.1
Sequence:
6; NC_000006.12 (29942532..29945870)
Diseases
Neoplasms
Malignant Neoplasms
Dysequilibrium Syndrome
Carcinoma
Leukemia
Graft-vs-host Disease
Melanoma
Autoimmune Reaction
Diabetes Mellitus
Hiv Infections
Diabetes Mellitus, Insulin-dependent
Malignant Paraganglionic Neoplasm
Arthritis
Acute Gvh Disease
Immunologic Deficiency Syndromes
Hepatitis
Autoimmune Diseases
Myeloid Leukemia, Chronic
Decreased Immunologic Activity [pe]
Cytomegalovirus Infections
Pathways
Immune Response
Pathogenesis
Sensitization
Secretion
Localization
Donor Selection
Transport
Cytolysis
Cell Activation
Cell Proliferation
Cell Recognition
Hypersensitivity
Gene Conversion
Translation
Complement-dependent Cytotoxicity
T Cell Activation
Viral Replication
Methylation
Cytokine Production
Glycosylation
PTMs
Cleavage
Glycosylation
Methylation
Phosphorylation
Biotinylation
Iodination
Ubiquitination
Demethylation
Decarboxylation
Citrullination
Acylation
Cysteinylation
Reduction
Acetylation
Oxidation
Deglycosylation
Research Areas
Adaptive Immunity
Cell Biology
Immunology
For details, visit: bosterbio.com/bosterbio-gene-info-cards/HLA-A
References
PMID: 2431040 by Wan A.M., et al. The primary structure of HLA-A32 suggests a region involved in formation of the Bw4/Bw6 epitopes.
PMID: 3496393 by Holmes N., et al. Multiple genetic mechanisms have contributed to the generation of the HLA- A2/A28 family of class I MHC molecules.
6 Publications of Boster HLA-A Antibodies & ELISA Kits
PubMed ID: 10.1371/journal.pone.0258817, PKI-587 enhances radiosensitization of hepatocellular carcinoma by inhibiting th...
PubMed ID: 10.1007/s10495-017-1391-1, Multi-targeted therapy of everolimus in Kaposi’s sarcoma associated herpes vir...
PubMed ID: , Performance of a multilayered small-diameter vascular scaffold dual-loaded with ...
PubMed ID: , IFN-γ enhances cell-mediated cytotoxicity against keratinocytes via JAK2/STAT1 ...