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3 Citations 16 Q&As
Facts about Keratin, type I cytoskeletal 14.
Human | |
---|---|
Gene Name: | KRT14 |
Uniprot: | P02533 |
Entrez: | 3861 |
Belongs to: |
---|
intermediate filament family |
CK14; CK-14; Cytokeratin 14; cytokeratin-14; EBS3; EBS4; K14; keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner); keratin 14; keratin, type I cytoskeletal 14; keratin-14; KRT14; NFJ
Mass (kDA):
51.561 kDA
Human | |
---|---|
Location: | 17q21.2 |
Sequence: | 17; NC_000017.11 (41582279..41586895, complement) |
Detected in the basal layer, lowered within the more apically located layers specifically in the stratum spinosum, stratum granulosum but is not detected in stratum corneum. Strongly expressed in the outer root sheath of anagen follicles but not in the germinative matrix, inner root sheath or hair. Found in keratinocytes surrounding the club hair during telogen.
Cytoplasm. Nucleus. Expressed in both as a filamentous pattern.
If you're planning to optimize your experiments using Boster Bio, you've come to the right place. We'll provide you with optimization tips, troubleshooting guides, and Steven Boster's history, among other things. Read on to find out how you can optimize your experiments and achieve superior results. There's no doubt that every researcher experiences difficulties in their experiments. The good news is that many of these errors are easily preventable by implementing the correct controls. Using these troubleshooting guides will help you to identify the most common sources of error.
In addition to primary antibodies, Boster Bio offers isotype controls and detection systems optimized for IHC. In addition to these, the company provides information on common questions and concerns from customers, including questions related to negative control conditions. Read on for some tips for optimizing your Boster Bio IHC tests for the KRT14 marker. Here are some of the most common questions related to Boster Bio products and procedures.
Flow cytometry is a powerful technique for studying cells in heterogeneous fluid mixtures. Boster Bio offers protocols for a variety of applications that include flow cytometry. These protocols provide a step-by-step overview of the flow cytometry process and can serve as a primer for new users. In addition to the protocols, you can find product datasheets and sample preparation guides from Boster Bio.
In his lifetime, Steven Boster developed hundreds of primary antibodies for various applications. His company has a unique history, earning him the nickname, "he who converts science in the lavatory". By the late 90s, Boster had become the largest catalog antibody manufacturer in China. His company also developed proprietary technology, PicoKine(tm), for the development of high-sensitivity ELISA kits. The company's products were hailed as "the best in their field" and he received multiple awards.
PMID: 6210150 by Marchuk D., et al. Remarkable conservation of structure among intermediate filament genes.
PMID: 2580298 by Marchuk D., et al. Complete sequence of a gene encoding a human type I keratin: sequences homologous to enhancer elements in the regulatory region of the gene.
*More publications can be found for each product on its corresponding product page