- Table of Content
The expression of MIF in sites of inflammation suggests a role as mediator in regulating the use of macrophages in host defense. Counteracts the anti- inflammatory action of glucocorticoids.
|Sequence:||22; NC_000022.11 (23894383..23895223)|
Secreted. Cytoplasm. Does not have a cleavable signal sequence and is secreted via a specialized, non-classical pathway. Secreted by macrophages upon stimulation by bacterial lipopolysaccharide (LPS), or by M.tuberculosis antigens.
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