PCBP2 Antibodies

AND PCBP2 ELISA kits, PCBP2 Proteins

Many biological assays use antibodies to detect PCBP2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PCBP2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PCBP2 antibodies...

We validate the specificity of these antibodies to PCBP2 by testing them on tissues known to express PCBP2 positively and negatively. Browse below to find the PCBP2 antibody that suites your experiment. We have 7 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PCBP2 Infographic by Boster Bio

All PCBP2 Products

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Applications

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Anti-Poly(rC)-binding protein 2 PCBP2 Antibody

Western blot analysis of extracts of various cell lines, using hnRNP E2/PCBP2 Rabbit pAb antibody at 1:1000 dilution

Immunofluorescence analysis of NIH-3T3 cells using hnRNP E2/PCBP2 Rabbit pAb at dilution of 1:100

Immunohistochemistry of paraffin-embedded mouse brain using hnRNP E2/PCBP2 Rabbit pAb at dilution of 1:100

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A02425
100ul

Anti-PCBP2/hnRNP E2 Antibody Picoband®

Western blot analysis of PCBP2/hnRNP E2 using anti-PCBP2/hnRNP E2 antibody (A02425-2)

IHC analysis of PCBP2/hnRNP E2 using anti-PCBP2/hnRNP E2 antibody (A02425-2)

Human, Mouse, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A02425-2
100 μg/vial

PCBP2 (NM_001098620) Human Recombinant Protein

Coomassie blue staining of purified PCBP2 protein

$1062
Cat # PROTQ15366
20 µg

Anti-PCBP2/hnRNP E2 Antibody Picoband® (monoclonal, 4B9C7)

Western blot analysis of PCBP2/hnRNP E2 using anti-PCBP2/hnRNP E2 antibody (M02425)

IF analysis of PCBP2/hnRNP E2 using anti-PCBP2/hnRNP E2 antibody (M02425)

Flow Cytometry analysis of PC-3 cells using anti-PCBP2/hnRNP E2 antibody (M02425)

Human, Mouse, Rat

Flow Cytometry, IF, ICC, WB

$370
Cat # M02425
100 μg/vial

Anti-PCBP2 Rabbit Monoclonal Antibody

Western blot analysis of PCBP2 using anti-PCBP2 antibody (M02425-1)

IHC analysis of PCBP2 using anti-PCBP2 antibody (M02425-1)

Human, Mouse, Rat

IP, IF, ICC, WB

$370
Cat # M02425-1
100 μl/vial

PCBP2 (NM_005016) Human Over-expression Lysate

PCBP2 Human Over-expression Lysates NM_001098620

Human

$628
Cat # LS005094
20 µg, 100 µg

Anti-hnRNP E2/PCBP2 Antibody Picoband®

Western blot analysis of hnRNP E2/PCBP2 using anti-hnRNP E2/PCBP2 antibody (A02425-3)

IF analysis of hnRNP E2/PCBP2 using anti-hnRNP E2/PCBP2 antibody (A02425-3) and anti-Tubulin Alpha antibody (M03989-3)

Flow Cytometry analysis of Hela cells using anti-hnRNP E2/PCBP2 antibody (A02425-3)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A02425-3
100 µg/vial

PCBP2 Overview

Facts about Poly(rC)-binding protein 2.

PCBP2 3D structure. Source: alphafold

Poly(rC)-binding protein 2 (PCBP2)

Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein.

Binds also poly(rU). Negatively regulates cellular antiviral responses mediated by MAVS signaling (PubMed:19881509).

Gene Information

Human
Gene Name:	PCBP2
Uniprot:	Q15366
Entrez:	5094

Family

Belongs to:

No superfamily

Alternative Names

alpha-CP2; Heterogeneous nuclear ribonucleoprotein E2; heterogenous nuclear ribonucleoprotein E2; hnRNP E2; hnRNP-E2; HNRPE2; MGC110998; poly(rC) binding protein 2; poly(rC)-binding protein 2

Molecular Weight

Mass (kDA):
38.58 kDA

Genomic Context


Human

Location:	12q13.13
Sequence:	12; NC_000012.12 (53452102..53481162)

Tissue Specificity

Detected in all tissues examined.

Subcellular Localizations

Nucleus. Cytoplasm. Loosely bound in the nucleus. May shuttle between the nucleus and the cytoplasm.

Diseases

Hepatitis
Hepatitis C
Carcinoma
Malignant Neoplasms
Hypoxia
Picornaviridae Infections
Malignant Neoplasm Of Breast
Fibrosis
Hepatitis A
Liver Carcinoma
Vesicular Stomatitis
Liver Neoplasms
Liver Cirrhosis

Hepatitis, Chronic
Neurodegenerative Disorders
Stomatitis
Innate Immune Response
Porcine Reproductive And Respiratory Syndrome
Malignant Neoplasm Of Prostate
Virus Diseases

Interacting Proteins

PCBP1
SNRPA
SRSF3

Pathways

Translation
Viral Replication
Cell Proliferation
Gene Silencing
Immune Response
Regulation Of Gene Expression
Reverse Transcription
Mrna Transcription
Cell Cycle
Mrna Stabilization
Innate Immune Response
Cell Growth
Rna Processing

Virion Assembly
Cell Activation
Localization
Cell Cycle Arrest
Decidualization
Mrna Splicing
Cell Death

PTMs

Cleavage
Phosphorylation

Reduction
Hydroxylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PCBP2

References

PMID: 7607214 by Leffers H., et al. Characterisation of two major cellular poly(rC)-binding human proteins, each containing three K-homologous (KH) domains.

PMID: 12414943 by Walter B.L., et al. Distinct poly(rC) binding protein KH domain determinants for poliovirus translation initiation and viral RNA replication.