PCCA Antibodies

AND PCCA ELISA kits, PCCA Proteins

Many biological assays use antibodies to detect PCCA, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PCCA in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PCCA antibodies...

We validate the specificity of these antibodies to PCCA by testing them on tissues known to express PCCA positively and negatively. Browse below to find the PCCA antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PCCA Infographic by Boster Bio

All PCCA Products

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Product

Figures

Specificity

Applications

Price

Anti-PCCA Antibody

Western blot analysis of extracts of various cell lines, using PCCA antibody at 1:3000 dilution

Mouse, Rat

$405
Cat # A03395
100ul

Anti-PCCA Mouse Monoclonal Antibody [Clone ID: OTI1E9]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PCCA (Right lane) cDNA for 48 hrs and lysed

Immunohistochemical staining of paraffin-embedded Human endometrium tissue within the normal limits using anti-PCCA mouse monoclonal antibody

Immunohistochemical staining of paraffin-embedded Human tonsil within the normal limits using anti-PCCA mouse monoclonal antibody

Human, Mouse, Rat

IHC, WB

$523
Cat # M03395
100 µl

PCCA (NM_000282) Human Over-expression Lysate

PCCA Human Over-expression Lysates NM_000282

Human

$960
Cat # LS005095
20 µg, 100 µg

Anti-PCCA Antibody Picoband®

Western blot analysis of PCCA using anti-PCCA antibody (A03395-1)

IHC analysis of PCCA using anti-PCCA antibody (A03395-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A03395-1
100 µg/vial

PCCA Overview

Facts about Propionyl-CoA carboxylase alpha chain, mitochondrial.

PCCA 3D structure. Source: alphafold

Propionyl-CoA carboxylase alpha chain, mitochondrial (PCCA)

Gene Information

Human
Gene Name:	PCCA
Uniprot:	P05165
Entrez:	5095

Family

Belongs to:

No superfamily

Alternative Names

EC 6.4.1; EC 6.4.1.3; pccA complementation group; PCCase alpha subunit; PCCase subunit alpha; propanoyl-CoA:carbon dioxide ligase alpha subunit; Propanoyl-CoA:carbon dioxide ligase subunit alpha; propionyl CoA carboxylase, alpha polypeptide; propionyl Coenzyme A carboxylase, alpha polypeptide; propionyl-CoA carboxylase alpha chain, mitochondrial

Molecular Weight

Mass (kDA):
80.059 kDA

Genomic Context


Human

Location:	13q32.3
Sequence:	13; NC_000013.11 (100089015..100530437)

Subcellular Localizations

Mitochondrion matrix.

Diseases

Propionic Acidemia
Acidemia
Inborn Errors Of Metabolism
Metabolic Diseases
Neoplasms
Comatose
Acidosis
Edema
Ketosis
Malignant Neoplasms
Methylmalonic Acidemia

Muscle Hypotonia
Colorectal Cancer
Metabolic Acidosis
Colorectal Neoplasms
Lethargy
Biotin Deficiency

Interacting Proteins

PCCB

Pathways

Transport
Translation
Excretion
Cell Proliferation
Vesicle Transport
Cell Development
Platelet Activation
Tropism
Biotin Transport
Reverse Transcription
Mrna Transcription

Coagulation
Epithelial Cell Development
Protein Folding
Fatty Acid Oxidation
Secretion

PTMs

Carboxylation
Biotinylation
Reduction

Hydroxylation
Cleavage
Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PCCA

References

PMID: 11592820 by Campeau E., et al. Structure of the PCCA gene and distribution of mutations causing propionic acidemia.

PMID: 2740237 by Lamhonwah A.-M., et al. Human mitochondrial propionyl-CoA carboxylase: localization of the N- terminus of the pro- and mature alpha chains in the deduced primary sequence of a full-length cDNA.