Protein regulator of cytokinesis 1 (PRC1)

Key regulator of cytokinesis which cross-links antiparrallel microtubules at a mean distance of 35 nM. Essential for controlling the spatiotemporal formation of the midzone and effective cytokinesis.

Required for KIF14 localization to the central spindle and midbody. Required to recruit PLK1 into the spindle.