Transcription factor SOX-2 (SOX2)

Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development like YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency.

May function as a change in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity).