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- Table of Contents
TIMP4 Antibodies
AND TIMP4 ELISA kits, TIMP4 Proteins
Many biological assays use antibodies to detect TIMP4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TIMP4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TIMP4 antibodies...
Designing a Western blot for TIMP4? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the TIMP4 Western Blot GuideTIMP4 Infographic by Boster Bio
All TIMP4 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$500
Cat # EZ0524
For 5 plates, 96 wells each
Cat # EZ0524
For 5 plates, 96 wells each
Human, Mouse, Rat
IHC, WB
$370
Cat # PA1078
100 μg/vial
Cat # PA1078
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A07131
100 μg/vial
Cat # A07131
100 μg/vial
Human
ELISA, WB
$370
Cat # PA1078-1
100 μg/vial
Cat # PA1078-1
100 μg/vial
Human, Mouse, Rat
ELISA
$480
Cat # EKC1566
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1566
1 kit, containing one 96-well plate and all necessary reagents
TIMP4 Overview
Facts about Metalloproteinase inhibitor 4.
Metalloproteinase inhibitor 4 (TIMP4)
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP- 9.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | TIMP4 |
| Uniprot: | Q99727 |
| Entrez: | 7079 |
Family
| Belongs to: |
|---|
| protease inhibitor I35 (TIMP) family |
Alternative Names
metalloproteinase inhibitor 4; TIMP metallopeptidase inhibitor 4; TIMP4; TIMP-4; tissue inhibitor of metalloproteinase 4; Tissue inhibitor of metalloproteinases 4
Molecular Weight
Mass (kDA):
25.503 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 3p25.2 |
| Sequence: | 3; NC_000003.12 (12153068..12158912, complement) |
Tissue Specificity
Abundant in heart and present at low levels in many other tissues.
Subcellular Localizations
Secreted.
Diseases
- Neoplasms
- Malignant Neoplasms
- Inflammation
- Hypertrophy
- Fibrosis
- Degenerative Polyarthritis
- Cell Invasion
- Tissue Adhesions
- Neoplasm Metastasis
- Neoplasm Invasiveness
- Carcinoma
- Heart Failure
- Malignant Paraganglionic Neoplasm
Pathways
- Pathogenesis
- Cell Proliferation
- Localization
- Cell Adhesion
- Proteolysis
- Methylation
- Angiogenesis
- Cell Migration
- Gene Silencing
- Osteoblast Differentiation
- Cellular Homeostasis
- Aging
- Zymogen Activation
PTMs
- Methylation
- Sulphation
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TIMP4
bosterbio.com/bosterbio-gene-info-cards/TIMP4
References
PMID: 8939999 by Greene J., et al. Molecular cloning and characterization of human tissue inhibitor of metalloproteinase 4.
PMID: 9693046 by Olson T.M., et al. Cloning of the human tissue inhibitor of metalloproteinase-4 gene (TIMP4) and localization of the TIMP4 and timp4 genes to human chromosome 3p25 and mouse chromosome 6, respectively.
3 Publications of Boster TIMP4 Antibodies & ELISA Kits
- PubMed ID: 10.1155/2019/7142438, Expressions of MMP-12, TIMP-4, and Neutrophil Elastase in PBMCs and Exhaled Brea...
- PubMed ID: 10.1155/2017/9542702, Paracrine Potential of the Human Adipose Tissue-Derived Stem Cells to Modulate B...
- PubMed ID: 31143784 , Expressions of MMP-12, TIMP-4, and Neutrophil Elastase in PBMCs and Exhaled Brea...
*More publications can be found for each product on its corresponding product page