Anti-Metalloproteinase inhibitor 4 TIMP4 Antibody Picoband®

Product Name

Anti-Metalloproteinase inhibitor 4 TIMP4 Antibody Picoband®

View all TIMP4 Antibodies

SKU/Catalog Number

PA1078

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Metalloproteinase inhibitor 4 TIMP4 Antibody catalog # PA1078. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Metalloproteinase inhibitor 4 TIMP4 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1078)

Host

Rabbit

Contents

Each vial contains antibody formulated with stabilizing components, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
*This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the conjugation method used. For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human TIMP4, different from the related rat sequence by two amino acids, and from the related mouse sequence by three amino acids.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA1078 is reactive to TIMP4 in Human, Mouse, Rat

Observed Molecular Weight

25 kDa

Calculated molecular weight

25.5 kDa

Background of TIMP4

Metalloproteinase inhibitor 4 is an enzyme that in humans is encoded by the TIMP4 gene. And this gene is mapped to chromosome 3p25. This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

PA1078 is guaranteed for IHC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Rat, Mouse
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Rat, Mouse

Positive Control

WB: Rat Kidney Tissue, MCF-7 Whole Cell
IHC: Rat Kidney Tissue, Human Mammary Cancer Tissue

Validation Images & Assay Conditions

See full target information TIMP4

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