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- Table of Contents
2 Citations 3 Q&As
1 Citations 1 Q&As
Facts about Tight junction protein ZO-2.
| Human | |
|---|---|
| Gene Name: | TJP2 |
| Uniprot: | Q9UDY2 |
| Entrez: | 9414 |

| Belongs to: |
|---|
| MAGUK family |

C9DUPq21.11; DFNA51; DUP9q21.11; MGC26306; tight junction protein 2 (zona occludens 2); Tight junction protein 2; TJP2; X104; X104tight junction protein ZO-2; ZO2; ZO-2; ZO2Friedreich ataxia region gene X104 (tight junction protein ZO-2); Zona occludens protein 2; Zonula occludens protein 2
Mass (kDA):
133.958 kDA

| Human | |
|---|---|
| Location: | 9q21.11 |
| Sequence: | 9; NC_000009.12 (69121006..69255208) |
This protein is found in epithelial cell junctions. Isoform A1 is abundant in the heart and brain. Detected in brain and skeletal muscle. It is present almost exclusively in normal tissues. Isoform C1 is expressed at high level in the kidney, pancreas, heart and placenta. Not detected in brain and skeletal muscle. Found in normal as well as in most neoplastic tissues.
Cell junction, adherens junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, tight junction. Nucleus. Also nuclear under environmental stress conditions and in migratory endothelial cells and subconfluent epithelial cell cultures.





PMID: 7951235 by Duclos F., et al. The Friedreich ataxia region: characterization of two novel genes and reduction of the critical region to 300 kb.
PMID: 11018256 by Chlenski A., et al. Organization and expression of the human zo-2 gene (tjp-2) in normal and neoplastic tissues.