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Highly unsaturated fatty acids (HUFA) play critical roles in many biological functions. It catalizes as well the introduction of a cis double bond in palmitate to produce the mono-unsaturated fatty acid sapienate, the most abundant fatty acid in sebum.
|fatty acid desaturase type 1 family|
|Sequence:||11; NC_000011.10 (61816203..61867354)|
Expressed in a wide array of tissues, highest expression is found in liver followed by brain, lung, heart, and retina. A lower level is found in breast tumor when compared with normal tissues; lowest levels were found in patients with poor prognostic index.
Endoplasmic reticulum membrane; Multi-pass membrane protein.