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- Table of Contents
Facts about Thioredoxin-interacting protein.
Functions as a transcriptional repressor, perhaps by acting as a bridge molecule between transcription factors and corepressor complexes, and over- expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells.
Human | |
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Gene Name: | TXNIP |
Uniprot: | Q9H3M7 |
Entrez: | 10628 |
Belongs to: |
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arrestin family |
HHCPA78; THIF; thioredoxin binding protein 2; thioredoxin interacting protein; Thioredoxin-binding protein 2; thioredoxin-interacting protein; upregulated by 1,25-dihydroxyvitamin D-3; VDUP1EST01027; Vitamin D3 up-regulated protein 1
Mass (kDA):
43.661 kDA
Human | |
---|---|
Location: | 1q21.1 |
Sequence: | 1; NC_000001.11 (145992435..145996579, complement) |
Cytoplasm.
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PMID: 8086474 by Chen K.-S., et al. Isolation and characterization of a novel cDNA from HL-60 cells treated with 1,25-dihydroxyvitamin D-3.
PMID: 17603038 by Liyanage N.P.M., et al. Regulation of the bioavailability of thioredoxin in the lens by a specific thioredoxin-binding protein (TBP-2).