Anti-60S ribosomal protein L11 RPL11 Antibody

RPL11 antibody

Boster Bio Anti-60S ribosomal protein L11 RPL11 Antibody catalog # A02901. Tested in WB,ICC applications. This antibody reacts with Human,Mouse,Rat.

Product Info Summary

SKU: A02901
Size: 100ul
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: ICC, WB

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Product Name

Anti-60S ribosomal protein L11 RPL11 Antibody

View all RPL11 Antibodies

SKU/Catalog Number

A02901

Size

100ul

Form

Liquid

Description

Boster Bio Anti-60S ribosomal protein L11 RPL11 Antibody catalog # A02901. Tested in WB,ICC applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-60S ribosomal protein L11 RPL11 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02901)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

Synthetic peptide, corresponding to amino acids 202-252 of Human E2F-2.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A02901 is reactive to RPL11 in Human, Mouse, Rat

Applications

A02901 is guaranteed for ICC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

20.252kDa

Background of RPL11

Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs. Also binds to double- and single-stranded DNA sequences in a specific manner and functions a transcription factor. Each of the RNA-binding domains specifically can bind solely to a single-stranded non-monotonous 5'-UUAG-3' sequence and also weaker to the single-stranded 5'-TTAGGG-3' telomeric DNA repeat. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats. Binding of RRM1 to DNA inhibits the formation of DNA quadruplex structure which may play a role in telomere elongation. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. May play a role in the regulation of the rhythmic expression of circadian clock core genes. Directly binds to the 3'UTR of CRY1 mRNA and induces CRY1 rhythmic translation. May also be involved in the regulation of PER2 translation.

Kajita Y., J. Biol. Chem. 270:22167-22175(1995).
Dempsey L.A., Genomics 49:378-384(1998).
Tolnay M., Biochem. J. 338:417-425(1999).
Grosset C., Cell 103:29-40(2000)

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:1000
ICC: 1:50-1:200

Validation Images & Assay Conditions

Gene/Protein Information For RPL11 (Source: Uniprot.org, NCBI)

Gene Name

RPL11

Full Name

60S ribosomal protein L11

Weight

20.252kDa

Superfamily

universal ribosomal protein uL5 family

Alternative Names

cell growth-inhibiting protein 34,60S ribosomal protein L11; CLL-associated antigen KW-12; DBA7; GIG34; ribosomal protein L11 RPL11 DBA7, GIG34, L11, uL5 ribosomal protein L11 60S ribosomal protein L11|CLL-associated antigen KW-12|cell growth-inhibiting protein 34|large ribosomal subunit protein uL5

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on RPL11, check out the RPL11 Infographic

RPL11 infographic

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In this infographic, you will see the following information for RPL11: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A02901-100ul

100ul

$405

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*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
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