Anti-CaMKII alpha/CAMK2A Antibody Picoband™

CAMK2A antibody

Boster Bio Anti-CaMKII alpha/CAMK2A Antibody Picoband™ catalog # A03241-1. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. Cited in 5 publication(s).

Product Info Summary

SKU: A03241-1
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: ELISA, WB

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Product Name

Anti-CaMKII alpha/CAMK2A Antibody Picoband™

View all CAMK2A Antibodies

SKU/Catalog Number

A03241-1

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-CaMKII alpha/CAMK2A Antibody Picoband™ catalog # A03241-1. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-CaMKII alpha/CAMK2A Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03241-1)

Host

Rabbit

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E. coli-derived human CaMKII alpha recombinant protein (Position: L392-R457).

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

A03241-1 is reactive to CAMK2A in Human, Mouse, Rat

Applications

A03241-1 is guaranteed for ELISA, WB Boster Guarantee

Observed Molecular Weight

50 kDa; 60 kDa

Calculated molecular weight

54.088kDa

Background of CAMK2A

MAX (Max protein), also called Myc-associated factor x, is the most conserved dimerization component of the MYC-MAX-MXD1 network of basic helix-loop-helix leucine zipper (bHLHZ) transcription factors that regulate cell proliferation, differentiation, and apoptosis. The conservation of the MAX sequence is particularly high in the bHLHZ domain, which is involved in protein-protein interactions and DNA binding. The MAX gene is located on chromosome 14q23 by fluorescence in situ chromosomal hybridization. Both quasisymmetric heterodimers resemble the symmetric MAX homodimer, albeit with marked structural differences in the coiled-coil leucine zipper regions that explain preferential homo- and heteromeric dimerization of these 3 evolutionarily related DNA-binding proteins. MAX acts as a classic tumor suppressor gene. Normal lymphocytes from patients showed absence of methylation of the MAX promoter and biallelic expression of MAX, which ruled out an imprinting-mediated effect on MAX expression. The ability of these cells to divide, differentiate, and apoptose in the absence of Max demonstrated for the first time that these processes can occur via Max- and possibly Myc-independent mechanisms.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml
Direct ELISA, 0.1-0.5μg/ml

Validation Images & Assay Conditions

Gene/Protein Information For CAMK2A (Source: Uniprot.org, NCBI)

Gene Name

CAMK2A

Full Name

Calcium/calmodulin-dependent protein kinase type II subunit alpha

Weight

54.088kDa

Superfamily

protein kinase superfamily

Alternative Names

calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha; calcium/calmodulin-dependent protein kinase II alpha; calcium/calmodulin-dependent protein kinase II alpha-B subunit; CaM kinase II alpha subunit; CaM Kinase II alpha; CaM kinase II subunit alpha; CAMK2A; CAMKAcalcium/calmodulin-dependent protein kinase type II subunit alpha; CaMK-II alpha subunit; CaMK-II subunit alpha; CaMKIINalpha; CaM-kinase II alpha chain; EC 2.7.11; EC 2.7.11.17; KIAA0968calcium/calmodulin-dependent protein kinase type II alpha chain CAMK2A CAMKA, CaMKIINalpha, CaMKIIalpha, MRD53, MRT63 calcium/calmodulin dependent protein kinase II alpha calcium/calmodulin-dependent protein kinase type II subunit alpha|CaM kinase II alpha subunit|CaM-kinase II alpha chain|CaMK-II alpha subunit|caM kinase II subunit alpha|caMK-II subunit alpha|calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha|calcium/calmodulin-dependent protein kinase II alpha-B subunit|calcium/calmodulin-dependent protein kinase type II alpha chain

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on CAMK2A, check out the CAMK2A Infographic

CAMK2A infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for CAMK2A: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

A03241-1 has been cited in 5 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Meng, X.,Fu, M.,Wang, S.,Chen, W.,Wang, J.,& Zhang, N.(2021). Naringin ameliorates memory deficits and exerts neuroprotective effects in a mouse model of Alzheimer‘s disease by regulating multiple metabolic pathways. Molecular Medicine Reports,23,332.https://doi.org/10.3892/mmr.2021.11971
Species: Mouse
A03241-1 usage in article: APP:WB, SAMPLE:HIPPOCAMPUS TISSUE, DILUTION:1:1000

Inhibition of CaMKII%u03B1 in the central nucleus of amygdala attenuates fentanyl-induced hyperalgesia in rats

Anti-Epileptic Effect of Ganoderma Lucidum Polysaccharides by Inhibition of Intracellular Calcium Accumulation and Stimulation of Expression of CaMKII ? in Epileptic Hippocampal Neurons

Li Z, Yin P, Chen J, Jin S, Liu J, Luo F. PLoS One. 2017 May 10;12(5):e0177412. doi: 10.1371/journal.pone.0177412. eCollection 2017. CaMKIIα may modulate fentanyl-induced hyperalgesia via a CeLC-PAG-RVM-spinal cord descending facilitative pain pat...

Sun Z, Niu R, Su K, Wang B, Wang J, Zhang J, Wang J. Arch Toxicol. 2010 May;84(5):353-61. Doi: 10.1007/S00204-009-0508-X. Epub 2010 Jan 6. Effects Of Sodium Fluoride On Hyperactivation And Ca2+ Signaling Pathway In Sperm From Mice: An In Vivo Study.

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1 Customer Q&As for Anti-CaMKII alpha/CAMK2A Antibody Picoband™

Question

We are currently using anti-CaMKII alpha/CAMK2A antibody A03241-1 for rat tissue, and we are satisfied with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it possible that the antibody can work on horse tissues as well?

Verified Customer

Verified customer

Asked: 2018-07-11

Answer

The anti-CaMKII alpha/CAMK2A antibody (A03241-1) has not been tested for cross reactivity specifically with horse tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in horse you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2018-07-11

Order DetailsPrice
A03241-1

100μg

$370
A03241-1-10ug

10μg sample (liquid)

$99
A03241-1-Biotin

100 μg Biotin conjugated

$570
A03241-1-Cy3

100 μg Cy3 conjugated

$570
A03241-1-Dylight488

100 μg Dylight488 conjugated

$570
A03241-1-Dylight550

100 μg Dylight550 conjugated

$570
A03241-1-Dylight594

100 μg Dylight594 conjugated

$570
A03241-1-FITC

100 μg FITC conjugated

$570
A03241-1-HRP

100 μg HRP conjugated

$570
A03241-1-APC

100 μg APC conjugated

$670
A03241-1-PE

100 μg PE conjugated

$670
A03241-1-carrier-free

Carrier Free

$370

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A03241-1
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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