Anti-CD206/MRC1 Antibody (Monoclonal, 31M03)

Anti-CD206/MRC1 Antibody (Monoclonal, 31M03)
View all MRC1 Antibodies

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
This antibody is supplied in a stabilized formulation.
Compatibility with conjugation reactions depends on the chemistry of the conjugation method used.
For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

31M03

180-200 kDa

The mannose receptor (Cluster of Differentiation 206,CD206) is a C-type lectin primarily present on the surface of macrophages,immature dendritic cells and liver sinusoidal endothelial cells,but is also expressed on the surface of skin cells such as human dermal fibroblasts and keratinocytes. It is mapped to 10p12.33. The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes,including cell-cell recognition,serum glycoprotein turnover,and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses,bacteria,and fungi so that they can be neutralized by phagocytic engulfment.