Anti-Growth hormone receptor/GHR Picoband™ Antibody

Growth Hormone R antibody

Boster Bio Anti-Growth hormone receptor/GHR Picoband™ Antibody catalog # A00698. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human.

Product Info Summary

SKU: A00698
Size: 100μg/vial
Reactive Species: Human
Host: Rabbit
Application: ELISA, Flow Cytometry, IF, ICC, WB

Product Name

Anti-Growth hormone receptor/GHR Picoband™ Antibody

View all Growth Hormone R Antibodies

SKU/Catalog Number

A00698

Size

100μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Growth hormone receptor/GHR Picoband™ Antibody catalog # A00698. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Growth hormone receptor/GHR Picoband™ Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00698)

Host

Rabbit

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Immunogen

E.coli-derived human Growth hormone receptor/GHR recombinant protein (Position: F19-P638).

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross Reactivity

No cross reactivity with other proteins.

Reactive Species

A00698 is reactive to GHR in Human

Applications

A00698 is guaranteed for ELISA, Flow Cytometry, IF, ICC, WB Boster Guarantee

Background of Growth Hormone R

Growth hormone receptor is a protein that in humans is encoded by the GHR gene. It is mapped to 5p13.1-p12. This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

Western blot, 0.25-0.5μg/ml, Human
Immunocytochemistry/Immunofluorescence, 2μg/ml, Human
Flow Cytometry, 1-3μg/1x106 cells, Human
Direct ELISA, 0.1-0.5μg/ml, Human

Validation Images & Assay Conditions

Gene/Protein Information For GHR (Source: Uniprot.Org, NCBI)

Uniprot ID

P10912

Gene ID

2690

Gene Name

GHR

Full Name

Growth hormone receptor

Weight

71.5kDa

Superfamily

type I cytokine receptor family

Alternative Names

GH receptor; GHBP; GHR; growth hormone binding protein; Growth Hormone R; growth hormone receptor; serum binding protein; Somatotropin receptor GHR GHBP, GHIP growth hormone receptor growth hormone receptor|GH receptor|growth hormone binding protein|serum binding protein|somatotropin receptor

*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".

For more info on GHR, check out the GHR Infographic

GHR infographic

We have 30,000+ of these available, one for each gene! check them out.

In this infographic you will see the following information for GHR: database IDs, super-family, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us [email protected]

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Conjugation

how to order through PO

Size

Total: $315

Size:100μg

SKU:A00698

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A00698
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$315.00

$50 fee for conjugation. Antibody size is reduced to 50ug.

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