Anti-Hu CD140a Purified PDGFRA Monoclonal Antibody

PDGFR alpha antibody

Boster Bio Anti-Hu CD140a Purified PDGFRA Monoclonal Antibody (Catalog# M00366-1). Tested in Flow Cytometry, ICC application(s). This antibody reacts with Human.

Product Info Summary

SKU: M00366-1
Size: 0.1 mg
Reactive Species: Human
Host: Mouse
Application: Flow Cytometry, ICC

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Product Name

Anti-Hu CD140a Purified PDGFRA Monoclonal Antibody

View all PDGFR alpha Antibodies

SKU/Catalog Number

M00366-1

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Hu CD140a Purified PDGFRA Monoclonal Antibody (Catalog# M00366-1). Tested in Flow Cytometry, ICC application(s). This antibody reacts with Human.

Storage & Handling

Store at 2-8°C. Do not freeze.

Cite This Product

Anti-Hu CD140a Purified PDGFRA Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00366-1)

Host

Mouse

Contents

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Clonality

Monoclonal

Clone Number

16A1

Isotype

Mouse IgG1 kappa

Immunogen

CD140a-transfected NIH 3T3 cells. The mouse monoclonal antibody 16A1 recognizes an extracellular epitope of CD140a / PDGF-RA, the 170 kDa alpha chain of platelet-derived growth factor receptor, which is widely expressed on a variety of mesenchymal-derived cells and plays pro-proliferative or anti-proliferative roles in various tumours.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M00366-1 is reactive to PDGFRA in Human

Applications

M00366-1 is guaranteed for Flow Cytometry, ICC Boster Guarantee

Observed Molecular Weight

42 kDa

Calculated molecular weight

122.67kDa

Background of PDGFR alpha

CD140a / PDGF-RA (platelet-derived growth factor receptor alpha) is a cell surface receptor for members of platelet-derived growth factor family, whose intracellular part contains a tyrosine kinase domain. CD140a forms homodimers, or heterodimerizes with CD140b / PDGF-RB. Whereas CD140b induces in different cell types their proliferation and migration, the role of CD140a is more controversial, with pro-proliferative or anti-proliferative effects. CD140a has early developmental functions, mediates mesodermal cell migration, and later acts in signaling associated in epithelial-mesenchymal interactions.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Flow cytometry: 2 μg/ml.

Validation Images & Assay Conditions

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Gene/Protein Information For PDGFRA (Source: Uniprot.org, NCBI)

Gene Name

PDGFRA

Full Name

Platelet-derived growth factor receptor alpha

Weight

122.67kDa

Superfamily

protein kinase superfamily

Alternative Names

alpha-type platelet-derived growth factor receptor; CD140 antigen-like family member A; CD140a antigen; CD140a; EC 2.7.10; EC 2.7.10.1; MGC74795; PDGF R alpha; PDGFR alpha; PDGFR2; PDGFRA; PDGFRA/BCR fusion; PDGF-R-alpha; platelet-derived growth factor receptor, alpha polypeptide; rearranged-in-hypereosinophilia-platelet derived growth factor receptor alphafusion protein; RHEPDGFRA PDGFRA CD140A, PDGFR-2, PDGFR2 platelet derived growth factor receptor alpha platelet-derived growth factor receptor alpha|CD140 antigen-like family member A|CD140a antigen|PDGF-R-alpha|alpha-type platelet-derived growth factor receptor|platelet-derived growth factor receptor 2|platelet-derived growth factor receptor, alpha polypeptide

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on PDGFRA, check out the PDGFRA Infographic

PDGFRA infographic

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In this infographic, you will see the following information for PDGFRA: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
M00366-1

0.1 mg

$305

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