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Product Info Summary
| SKU: | M01025-2 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Mouse |
| Application: | Flow Cytometry, IHC, ICC |
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Product info
Product Name
Anti-Hu CD209 Purified Monoclonal Antibody
SKU/Catalog Number
M01025-2
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Hu CD209 Purified Monoclonal Antibody (Catalog# M01025-2). Tested in Flow Cytometry, IHC, ICC application(s). This antibody reacts with Human.
Storage & Handling
Store at 2-8°C. Do not freeze.
Cite This Product
Anti-Hu CD209 Purified Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01025-2)
Host
Mouse
Contents
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Clonality
Monoclonal
Clone Number
UW60.1
Isotype
Mouse IgG2a
Immunogen
CD209-His-tagged fusion protein. The mouse monoclonal antibody UW60.1 recognizes an extracellular epitope of human CD209 (DC-SIGN), a 44 kDa transmembrane receptor, expressed on the surface of dendritic cells and macrophages.
Reactive Species
M01025-2 is reactive to CD209 in Human
Observed Molecular Weight
42 kDa
Calculated molecular weight
45.8 kDa
Background of CD209
CD209, also known as DC-SIGN (dendritic cell-specific ICAM-3-grabbing nonintegrin) is a transmembrane receptor expressed on the surface of dendritic cells and macrophages, which recognizes numerous pathogens ranging from parasites to viruses. Its N-terminal domain is transmembrane, whereas a tandem-repeat neck domain and the C terminal C-type lectin carbohydrate recognition domain have dual function as a pathogen recognition receptor and a cell adhesion receptor. The neck region is responsible for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. A ligand of CD209 is also CD50 (ICAM-3).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M01025-2 is guaranteed for Flow Cytometry, IHC, ICC Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Flow cytometry: 1-4 μg/ml.
Validation Images & Assay Conditions
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Separation of human myeloid cells (red-filled) from lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human stimulated (GM-CSF+IL-4) peripheral blood mononuclear cells stained using anti-human CD209 (UW60.1) purified antibody (concentration in sample 0.6 µg/ml, GAM APC).
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Flow cytometry surface staining pattern of human stimulated (GM-CSF+IL-4) peripheral blood mononuclear cells stained using anti-human CD209 (UW60.1) purified antibody (concentration in sample 0.6 µg/ml, GAM APC).
Specific Publications For Anti-Hu CD209 Purified Monoclonal Antibody (M01025-2)
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