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- Table of Contents
CD209 antigen Antibodies
AND CD209 ELISA kits, CD209 antigen Proteins
Many biological assays use antibodies to detect CD209 antigen, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CD209 antigen in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CD209 antigen antibodies...
Designing a Western blot for CD209 antigen? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CD209 Western Blot GuideDesigning an IHC experiment for CD209 antigen? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the CD209 IHC GuideCD209 Infographic by Boster Bio
All CD209 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01025-4
100 μg
Cat # M01025-4
100 μg
CD209 Overview
Facts about CD209 antigen.
CD209 antigen (CD209)
Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune reaction. Thought to mediate the endocytosis of pathogens that are subsequently degraded in lysosomal compartments.
The receptor returns to the cell membrane surface and the pathogen-derived antigens are introduced to resting T-cells through MHC class II proteins to initiate the adaptive immune reaction. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CD209 |
| Uniprot: | Q9NNX6 |
| Entrez: | 30835 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
CD209 antigendendritic cell-specific intracellular adhesion molecules (ICAM)-3 grabbingnon-integrin; CD209 molecule; CD209; CDSIGNHIV gpl20-binding protein; CLEC4L; CLEC4LC-type lectin domain family 4 member L; DCSIGN; DC-SIGN; DC-SIGN1; DC-SIGN1C-type lectin domain family 4, member L; DC-SIGNMGC129965; Dendritic cell-specific ICAM-3-grabbing non-integrin 1
Molecular Weight
Mass (kDA):
45.775 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19p13.2 |
| Sequence: | 19; NC_000019.10 (7739993..7747609, complement) |
Tissue Specificity
Predominantly expressed in dendritic cells and in DC-residing tissues. Also found in placental macrophages, endothelial cells of placental vascular channels, peripheral blood mononuclear cells, and THP-1 monocytes.
Subcellular Localizations
[Isoform 1]: Cell membrane; Single-pass type II membrane protein.; [Isoform 2]: Cell membrane; Single-pass type II membrane protein.; [Isoform 3]: Cell membrane; Single-pass type II membrane protein.; [Isoform 4]: Cell membrane; Single-pass type II membrane protein.; [Isoform 5]: Cell membrane; Single-pass type II membrane protein.; [Isoform 6]: Secreted.; [Isoform 7]: Secreted.; [Isoform 8]: Secreted.; [Isoform 9]: Secreted.; [Isoform 10]: Secreted.; [Isoform 11]: Secreted.; [Isoform 12]: Secreted.
Diseases
- Tissue Adhesions
- Hiv Infections
- Tuberculosis
- Inflammation
- Neoplasms
- Dengue Fever
- Malignant Neoplasms
- Immunologic Deficiency Syndromes
- Tuberculosis, Pulmonary
- Virus Diseases
- Innate Immune Response
- Infective Disorder
- Mycoses
Interacting Proteins
- VAC14
Pathways
- Immune Response
- Pathogenesis
- Secretion
- Phagocytosis
- Endocytosis
- Cell Proliferation
- T Cell Proliferation
- Cell Differentiation
- Glycosylation
- Inflammatory Response
- Innate Immune Response
- Cell Adhesion
- Macrophage Activation
PTMs
- Phosphorylation
- Glycosylation
- Methylation
- Deglycosylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CD209
bosterbio.com/bosterbio-gene-info-cards/CD209
References
PMID: 1518869 by Curtis B.M., et al. Sequence and expression of a membrane-associated C-type lectin that exhibits CD4-independent binding of human immunodeficiency virus envelope glycoprotein gp 120.
PMID: 10975799 by Soilleux E.J., et al. DC-SIGN, a related gene, DC-SIGNR, and CD23 form a cluster on 19p13.
1 Publications of Boster CD209 antigen Antibodies & ELISA Kits
- PubMed ID: -, Tongtian Ni,Lili Xu,Silei Sun et al.Fluid Resuscitation via Colon Alleviates Sys...
*More publications can be found for each product on its corresponding product page